Exposure of cells to high voltage electric pulses increases transiently membrane
permeability through membrane electroporation. Electroporation can be reversible and is …

This review summarizes the use of high-voltage electrical pulses (HVEPs) in clinical
oncology to treat solid tumors with irreversible electroporation (IRE) and …

When high-amplitude, short-duration pulsed electric fields are applied to cells and tissues,
the permeability of the cell membranes and tissue is increased. This increase in permeability …

Purpose To provide an overview of current clinical results of irreversible electroporation
(IRE), a novel, nonthermal tumor ablation technique that uses electric pulses to induce cell …

Background Despite promising treatments for breast cancer, mortality rates remain high and
treatments for metastatic disease are limited. High-frequency irreversible electroporation (H …

Electric fields are among physical stimuli that have revolutionized therapy. Occurring
endogenously or exogenously, the electric field can be used as a trigger for controlled drug …

PURPOSE: Treatment of unresectable locally advanced pancreatic cancer (LAPC) usually
includes chemotherapy and/or radiation therapy in an attempt to downstage these tumors to …

Background Locally advanced pancreatic cancer (LAPC) is associated with a very poor
prognosis. Current palliative (radio) chemotherapy provides only a marginal survival benefit …

Simple Summary Electrochemotherapy and irreversible electroporation are primarily used
for treating patients with cutaneous and subcutaneous tumors and pancreatic cancer …

Purpose: Local tumor ablation through irreversible electroporation (IRE) may offer a novel
therapeutic option for locally advanced pancreatic cancer (LAPC). It may also serve as a …