The therapeutic landscape of chronic myeloid leukemia (CML) has profoundly changed over
the past 7 years. Most patients with chronic phase (CP) now have a normal life expectancy …

Management of chronic myeloid leukemia (CML) in advanced phases remains a challenge
also in the era of tyrosine kinase inhibitors (TKIs) treatment. Cytogenetic clonal evolution …

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm and was the first
neoplastic disease associated with a well-defined genotypic anomaly―the presence of the …

Abstract Background: Philadelphia chromosome-positive (Ph+) advanced leukemias,
including acute myeloid leukemia (AML) and chronic myeloid leukemia (CML) in myeloid …

1St James's University Hospital, Leeds, 2Imperial College, London, 3University of
Southampton, Southampton, 4University Hospital, Nottingham, 5University Hospital of …

Chronic myeloid leukemia (CML) is usually diagnosed in chronic phase, yet there is a small
percentage of patients that is diagnosed in accelerated phase or blast crisis. Due to this …

Background Chronic myeloid leukaemia (CML) is a rare disease in children. The frequency
and outcome of children evolving to accelerated phase (AP) or blastic phase (BP) under …

Although the tyrosine kinase inhibitor (TKI) era has brought great improvement in outcome in
chronic myelogenous leukemia (CML), prognosis of accelerated phase or myeloid blast …

The purpose of this study was to identify the incidence, causes and impact of non-adherence
to oral and subcutaneous chronic treatments for patients with polycythemia vera or essential …

Background: In the last two decades, tyrosine kinase inhibitors (TKIs) and advances in
molecular diagnostics have revolutionized management and long-term clinical outcomes in …