To comprehend the complexity of cancer, the biological characteristics acquired during the
initiation and progression of tumours were classified as the'hallmarks of cancer'. Intravital …

Microscopic imaging techniques to visualize cellular behaviors in their natural environment
play a pivotal role in biomedical research. Here, we review how recent technical advances …

Graded index (GRIN) lenses are commonly used for compact imaging systems. It is not
widely appreciated that the ion-exchange process that creates the rotationally symmetric …

Although most nanofabrication techniques can control nano/micro particle (NMP) size over a
wide range, the majority of NMPs for biomedical applications exhibits a diameter of~ 100 …

Rationale: High-resolution imaging of the heart in vivo is challenging owing to the difficulty in
accessing the heart and the tissue motion caused by the heartbeat. Objective: Here, we …

Optical fiber-based high-resolution fluorescence imaging techniques have promising
applications in clinical practice and preclinical research using animals. Here we review the …

Recent advances in label-free histology promise a new era for real-time diagnosis in
neurosurgery. Deep learning using autofluorescence is promising for tumor classification …

Skyrmions are topologically protected quasiparticles, originally studied in condensed-matter
systems and recently in photonics, with great potential in high-density information storage …

Background & Aims Caspase recruitment domain 9 (CARD9) is an adaptor protein that
integrates signals downstream of pattern recognition receptors. CARD9 has been …

Multiphoton microscopy of cellular autofluorescence and second harmonic generation from
collagen facilitates imaging of living cells and tissues without the need for additional …