Hepatic insulin resistance, metabolic syndrome and cardiovascular disease

R Meshkani, K Adeli - Clinical biochemistry, 2009 - Elsevier
BACKGROUND: The metabolic syndrome is a constellation of common metabolic disorders
that is associated with cardiovascular disease. Insulin resistance has a central role in the …

Recent advances in physiological lipoprotein metabolism

I Ramasamy - Clinical Chemistry and Laboratory Medicine (CCLM), 2014 - degruyter.com
Research into lipoprotein metabolism has developed because understanding lipoprotein
metabolism has important clinical indications. Lipoproteins are risk factors for cardiovascular …

Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

S Acton, A Rigotti, KT Landschulz, S Xu, HH Hobbs… - Science, 1996 - science.org
High density lipoprotein (HDL) and low density lipoprotein (LDL) are cholesterol transport
particles whose plasma concentrations are directly (LDL) and inversely (HDL) correlated …

Relation of triglyceride metabolism and coronary artery disease. Studies in the postprandial state.

JR Patsch, G Miesenböck, T Hopferwieser… - … and Thrombosis: A …, 1992 - Am Heart Assoc
The status of fasting triglycerides as a risk factor for coronary artery disease (CAD) has been
considered weak because in multivariate analyses, triglycerides tend to be eliminated by …

A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism

A Rigotti, BL Trigatti, M Penman… - Proceedings of the …, 1997 - National Acad Sciences
Plasma high density lipoprotein (HDL), which protects against atherosclerosis, is thought to
remove cholesterol from peripheral tissues and to deliver cholesteryl esters via a selective …

High-density lipoprotein cholesterol as a predictor of coronary heart disease risk. The PROCAM experience and pathophysiological implications for reverse …

G Assmann, H Schulte, A von Eckardstein, Y Huang - Atherosclerosis, 1996 - Elsevier
The incidence of coronary heart disease (CHD) was assessed via the Prospective
Cardiovascular Münster (PROCAM) study in 19 698 volunteer subjects aged between 16 …

Endothelial and antithrombotic actions of HDL

C Mineo, H Deguchi, JH Griffin, PW Shaul - Circulation research, 2006 - Am Heart Assoc
It is well recognized that high-density lipoprotein (HDL)-cholesterol is antiatherogenic and
serves a role in mediating cholesterol efflux from cells. However, HDL has multiple …

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors

MJ Chapman, W Le Goff, M Guerin… - European heart …, 2010 - academic.oup.com
Subnormal plasma levels of high-density lipoprotein cholesterol (HDL-C) constitute a major
cardiovascular risk factor; raising low HDL-C levels may therefore reduce the residual …

Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein …

M Navab, SS Imes, SY Hama… - The Journal of …, 1991 - Am Soc Clin Investig
Incubation of cocultures of human aortic endothelial (HAEC) and smooth muscle cells
(HASMC) with LDL in the presence of 5-10% human serum resulted in a 7.2-fold induction of …

Cardiovascular disease after renal transplantation.

BL Kasiske, C Guijarro, ZA Massy… - Journal of the …, 1996 - journals.lww.com
Although cardiovascular disease is a major cause of morbidity and mortality after renal
transplantation, its pathogenesis and treatment are poorly understood. We conducted …