Advances of lab-on-a-chip in isolation, detection and post-processing of circulating tumour cells

L Yu, SR Ng, Y Xu, H Dong, YJ Wang, CM Li - Lab on a Chip, 2013 - pubs.rsc.org
Circulating tumour cells (CTCs) are shed by primary tumours and are found in the peripheral
blood of patients with metastatic cancers. Recent studies have shown that the number of …

The latest advances on nonlinear insulator-based electrokinetic microsystems under direct current and low-frequency alternating current fields: a review

BH Lapizco-Encinas - Analytical and Bioanalytical Chemistry, 2022 - Springer
This review article presents an overview of the evolution of the field of insulator-based
dielectrophoresis (iDEP); in particular, it focuses on insulator-based electrokinetic (iEK) …

Continuous separation of DNA molecules by size using insulator-based dielectrophoresis

PV Jones, GL Salmon, A Ros - Analytical chemistry, 2017 - ACS Publications
Separation of nucleic acids has long served as a central goal of analytical research.
Innovations in this field may soon enable the development of rapid, on-site sequencing …

Controlled transport of individual microparticles using dielectrophoresis

MA Zaman, P Padhy, M Wu, W Ren, MA Jensen… - Langmuir, 2022 - ACS Publications
A dielectrophoretic device employing a planar array of microelectrodes is designed for
controlled transport of individual microparticles. By exciting the electrodes in sequence, a …

Insulator based dielectrophoresis: Micro, nano, and molecular scale biological applications

P Benhal, D Quashie, Y Kim, J Ali - Sensors, 2020 - mdpi.com
Insulator based dielectrophoresis (iDEP) is becoming increasingly important in emerging
biomolecular applications, including particle purification, fractionation, and separation …

Quantitative dielectrophoretic tracking for characterization and separation of persistent subpopulations of Cryptosporidium parvum

YH Su, M Tsegaye, W Varhue, KT Liao, LS Abebe… - Analyst, 2014 - pubs.rsc.org
Microbial persistence to antibiotics is attributed to subpopulations with phenotypic variations
that cause a spread of susceptibility levels, leading to the recurrence of infections and …

Review of dielectrophoretic manipulation of micro and nanomaterials: Fundamentals, recent developments, and challenges

T Ghomian, J Hihath - IEEE Transactions on Biomedical …, 2022 - ieeexplore.ieee.org
This paper reviews the state-of-the-art methods of dielectrophoresis for micro-and
nanomaterial manipulation. Dielectrophoresis is a well-known technique for material …

Design of a novel optimized microfluidic channel for CTCs separation utilizing a combination of TSAWs and DEP methods

R Derakhshan, A Mahboubidoust, A Ramiar - Chemical Engineering and …, 2021 - Elsevier
Circulating tumor cells are malignant cells shed into the vasculature or lymphatics from a
primary tumor and are carried around the body in the blood circulation. Separation of these …

Selective trapping of single mammalian breast cancer cells by insulator-based dielectrophoresis

S Bhattacharya, TC Chao, N Ariyasinghe… - Analytical and …, 2014 - Springer
The trapping or immobilization of individual cells at specific locations in microfluidic
platforms is essential for single cell studies, especially those requiring cell stimulation and …

Dielectrophoretic sorting of membrane protein nanocrystals

BG Abdallah, TC Chao, C Kupitz, P Fromme, A Ros - ACS nano, 2013 - ACS Publications
Structure elucidation of large membrane protein complexes is still a considerable challenge,
yet is a key factor in drug development and disease combat. Femtosecond …