Purpose To develop a guideline to improve the accuracy of immunohistochemical (IHC)
estrogen receptor (ER) and progesterone receptor (PgR) testing in breast cancer and the …

CA 125 also known as mucin 16 or MUC16 is a large membrane glycoprotein belonging to
the wide mucin family, encoded by the homonymous MUC16 gene. Following its discovery …

Abstract Background: Updated National Academy of Clinical Biochemistry (NACB)
Laboratory Medicine Practice Guidelines for the use of tumor markers in the clinic have been …

Background: Although multiple serum-based tumor markers have been described for breast
cancer, such as CA 15-3, BR 27.29 (CA27. 29), carcinoembryonic antigen (CEA), tissue …

Recommendations are presented for the routine clinical use of serum and tissue-based
markers in the diagnosis and management of patients with breast cancer. Their low …

Tumor markers are assuming a growing role in all aspects of cancer care, starting from
screening to follow-up after treatment, and their judicious application in clinical practice …

Background: Increasing interest in implementing the practice of evidence-based medicine in
oncology has encouraged the development of clinical guidelines, many of which include …

Background: Unpredictable efficacy and toxicity are hallmarks of most anticancer therapies.
Predictive markers are factors that are associated with response or resistance to a particular …

Background: The objectives of this study were to determine whether a single result for total
prostate-specific antigen (tPSA) can be used confidently to guide the need for prostate …

Background: This report presents updated National Academy of Clinical Biochemistry
Laboratory Medicine Practice Guidelines summarizing quality requirements for the use of …