The development of mesh nebulizer technology has expanded the ability to deliver medical
aerosols to infants and small children via nasal cannula and prongs. Mesh nebulizers do not …

Purpose Improving the deep lung delivery of aerosol surfactant therapy (AST) with a dry
powder formulation may enable significant reductions in dose while providing improved …

Objectives The efficient delivery of drugs from dry powder inhaler (DPI) formulations is
associated with the complex interaction between the device design, drug formulations, and …

Pharmaceutical aerosol systems present a significant challenge to computational fluid
dynamics (CFD) modeling based on the need to capture multiple levels of turbulence …

The vibrating mesh nebulizer (VMN) has gained popularity for its compactness and
noiselessness. This study investigates the impact of different air inlet structures on the …

There is a current medical need for a dry powder aerosol delivery device that can be used to
efficiently and consistently administer high dose therapeutics, such as inhaled antibiotics …

Purpose The objective of this study was to incorporate a passive cyclic loading strategy into
the infant air-jet dry powder inhaler (DPI) in a manner that provides high efficiency aerosol …

Purpose The objective of this study was to implement computational fluid dynamics (CFD)
simulations and aerosol characterization experiments to determine best-case spray drying …

Background: An infant air-jet dry powder inhaler (DPI) platform has recently been developed
that in combination with highly dispersible spray-dried powder formulations can achieve …

The objective of this study was to characterize the effects of multiple nasal prong interface
configurations on nasal depositional loss of pharmaceutical aerosols in a preterm infant …