Pyrazole is a five-membered aromatic heterocyclic ring with two adjacent nitrogen atoms C 3
H 3 N 2 H. The presence of this nucleus in pharmacological agents of various therapeutic …

Cancer is one of the leading health hazards and the prominent cause of death in the world.
A number of anticancer agents are currently in clinical practice and used for treatment of …

Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …

The combination of heterocycles offers a new opportunity to create novel multicyclic
compounds having improved biological activity. Coumarins are ubiquitous natural …

A series of forty different pyrazole containing benzimidazole hybrids (6–45) have been
designed, synthesized and evaluated for their potential anti-proliferative activity against …

Fms-like tyrosine kinase 3 (FLT3) is an important member of the class III receptor tyrosine
kinase (RTK) family, which is involved in the proliferation of hematopoietic cells and …

A series of new pyrazolo-benzothiazole hybrids (7–26) were synthesised and screened for
their cytotoxic activity towards several cancer cell lines [colon (HT-29), prostate (PC-3), lung …

In an aim at developing new antiproliferative agents, new series of benzothiazole/
benzoxazole and/or benzimidazole substituted pyrazole derivatives 11a-c, 12a-c and 13a-c …

This review-based study presents the anticancer potential of pyrazole-based copper
complexes, aiming to evaluate their mechanistic action at the molecular level and find …

A novel continuous‐flow approach for the synthesis of fluoroalkyl‐substituted
diazomethanes has been developed. Utilizing a cheap, self‐made microreactor fluoroalkyl …