Copper is an indispensable micronutrient for the development and replication of all
eukaryotes, and its redox properties are both harmful and beneficial to cells. An imbalance …

Copper (Cu) redox state has been an important issue in biology and toxicology research, but
many research gaps remain to be explored due to the limitations in the detecting techniques …

One of the main causes of heart failure is cardiomyopathies. Among them, the most common
is hypertrophic cardiomyopathy (HCM), characterized by thickening of the left ventricular …

Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious
manifestations. Management has traditionally comprised therapies to palliate symptoms and …

Abstract Purpose of Review Hypertrophic cardiomyopathy (HCM) is a common inherited
cardiac condition with potential for severe complications including sudden cardiac death …

Copper is an essential heavy metal for diverse biological functions but toxic in excess.
Consequently, a tightly regulated protein system is required to ensure adequate intracellular …

Hypertrophic cardiomyopathy (HCM) is characterized by abnormal growth of the
myocardium with myofilament disarray and myocardial hyper-contractility, leading to left …

铜是必需微量元素, 参与多种生物过程, 包括抗氧化防御, 神经肽合成和免疫功能. 然而,
铜也是有毒金属, 参与氧化应激和炎症反应. 目前, 人体内铜是否促进衰老相关疾病的发展仍不 …