Progressive multifocal leukoencephalopathy and the spectrum of JC virus-related disease

I Cortese, DS Reich, A Nath - Nature Reviews Neurology, 2021 - nature.com
Progressive multifocal leukoencephalopathy (PML) is a devastating CNS infection caused
by JC virus (JCV), a polyomavirus that commonly establishes persistent, asymptomatic …

Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis

CS Tan, IJ Koralnik - The Lancet Neurology, 2010 - thelancet.com
Progressive multifocal leukoencephalopathy (PML) is a rare but often fatal brain disease
caused by reactivation of the polyomavirus JC. Knowledge of the characteristics of PML has …

Progressive multifocal leukoencephalopathy: current treatment options and future perspectives

D Pavlovic, AC Patera, F Nyberg… - Therapeutic …, 2015 - journals.sagepub.com
Progressive multifocal leukoencephalopathy (PML) is a rare but debilitating and frequently
fatal viral disease of the central nervous system, primarily affecting individuals with …

Rituximab-associated progressive multifocal leukoencephalopathy in rheumatoid arthritis

DB Clifford, B Ances, C Costello… - Archives of …, 2011 - jamanetwork.com
Objective To describe the development of progressive multifocal leukoencephalopathy
(PML) in patients with rheumatoid arthritis (RA) treated with rituximab. Design Case study …

HIV-associated opportunistic infections of the CNS

IL Tan, BR Smith, G von Geldern, FJ Mateen… - The Lancet …, 2012 - thelancet.com
Survival in people infected with HIV has improved because of an increasingly powerful array
of antiretroviral treatments, but neurological symptoms due to comorbid conditions, including …

Progressive multifocal leukoencephalopathy and other forms of JC virus disease

BJ Brew, NWS Davies, P Cinque, DB Clifford… - Nature Reviews …, 2010 - nature.com
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the brain
caused by the JC virus (JCV). PML usually occurs via reactivation of JCV when an immune …

Progressive multifocal leukoencephalopathy in HIV-1 infection

P Cinque, IJ Koralnik, S Gerevini, JM Miro… - The Lancet infectious …, 2009 - thelancet.com
Progressive multifocal leukoencephalopathy is caused by the JC polyomavirus (JCV) and is
one of the most feared complications of HIV-1 infection. Unlike other opportunistic infections …

The human JC polyomavirus (JCPyV): virological background and clinical implications

HH Hirsch, P Kardas, D Kranz, C Leboeuf - Apmis, 2013 - Wiley Online Library
JC polyomavirus (JCPyV) was the first of now 12 PyVs detected in humans, when in 1964,
PyV particles were revealed by electron microscopy in progressive multifocal …

Identification and characterization of mefloquine efficacy against JC virus in vitro

M Brickelmaier, A Lugovskoy… - Antimicrobial agents …, 2009 - Am Soc Microbiol
Progressive multifocal leukoencephalopathy (PML) is a rare but frequently fatal disease
caused by the uncontrolled replication of JC virus (JCV), a polyomavirus, in the brains of …

European perspective on human polyomavirus infection, replication and disease in solid organ transplantation

HH Hirsch, N Babel, P Comoli, V Friman… - Clinical Microbiology …, 2014 - Wiley Online Library
Human polyomaviruses (HP yVs) are a growing challenge in immunocompromised patients
in view of the increasing number of now 12 HP yV species and their diverse disease …