Excessive sugar consumption is increasingly considered as a contributor to the emerging
epidemics of obesity and the associated cardiometabolic disease. Sugar is added to the diet …

Simple Summary For mammalian cells, glucose is a major source of energy. In the presence
of oxygen, a complete breakdown of glucose generates 36 molecules of ATP from one …

It is long recognized that cancer cells display increased glucose uptake and metabolism. In
a rate-limiting step for glucose metabolism, the glucose transporter (GLUT) proteins facilitate …

An important hallmark in cancer cells is the increase in glucose uptake. GLUT1 is an
important target in cancer treatment because cancer cells upregulate GLUT1, a membrane …

It has been known for 80years that cancer cell growth in an energy-related process
supported by an increased glucose metabolism. This phenomenon suggests a need for a …

Despite the long‐known fact that the facilitative glucose transporter GLUT1 is one of the key
players safeguarding the increase in glucose consumption of many tumor entities even …

Tumor cells exhibit elevated levels of glucose uptake, a phenomenon that has been
capitalized upon for the prognostic and diagnostic imaging of a wide range of cancers using …

Background Glucose transporter 1 (GLUT1) plays a critical role in tumorigenesis and tumor
progression in multiple cancer types. However, the specific function and clinical significance …

Prostate cancer (PCa) is the most common male malignancy and the fifth leading cause of
cancer death in men worldwide. Prostate cancer cells are characterized by a hybrid …

Prostate cancer is the second most common cancer in men worldwide, with a wide spectrum
of biologic behavior ranging from indolent low-risk disease to highly aggressive castration …