Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components
The invention provides for delivery, engineering and optimization of systems, methods, and
compositions for manipulation of sequences and/or activities of target sequences. Provided …
compositions for manipulation of sequences and/or activities of target sequences. Provided …
CRISPR enzyme mutations reducing off-target effects
F Zhang, L Gao, B Zetsche, I Slaymaker - US Patent 12,123,032, 2024 - Google Patents
DODQJNMQWMSYGS-QPLCGJKRSA-N 4-[(z)-1-[4-[2-(dimethylamino) ethoxy] phenyl]-1-
phenylbut-1-en-2-yl] phenol Chemical compound C= 1C= C (O) C= CC= 1C (/CC)= C (C …
phenylbut-1-en-2-yl] phenol Chemical compound C= 1C= C (O) C= CC= 1C (/CC)= C (C …