Invasive fungal infections constitute a serious threat to an ever-growing population of
immunocompromised individuals and other individuals at risk. Traditional diagnostic …

Invasive candidiasis (IC) is a significant cause of morbidity and mortality. Diagnosis relies on
culture-based methods, which lack sensitivity and delay diagnosis. We conducted a …

Background. Candidemia is common and associated with high morbidity and mortality;
changes in population-based incidence rates have not been reported. Methods. We …

Signals from the intestinal microbiota are important for normal host physiology; alteration of
the microbiota (dysbiosis) is associated with multiple disease states. We determined the …

Background. The sensitivity of blood cultures for diagnosing invasive candidiasis (IC) is
poor. Methods. We performed a validated Candida real-time polymerase chain reaction …

Invasive fungal infections are a growing problem in critically ill patients and are associated
with increased morbidity and mortality. Most of them are due to Candida species, especially …

Intestinal microbiota determine severity of myocardial infarction in rats. We determined
whether low molecular weight metabolites derived from intestinal microbiota and transported …

Candida species are the 4th most common cause of nosocomial bloodstream infections in
North America. It is not widely appreciated, however, that many of these infections are …

The focus of this review is the evolution of biochemical phenotypic yeast identification
methods with emphasis on conventional approaches, rapid screening tests, chromogenic …

PCR is a very appealing technology for the detection of human pathogens, but the detection
of fungal pathogens is particularly challenging. Fungi have cell walls that impede the …