The involvement of limbic structures in typical and atypical absence epilepsy

FY Onat, G van Luijtelaar, A Nehlig, OC Snead III - Epilepsy Research, 2013 - Elsevier
Typical and atypical seizures of absence epilepsy are thought to be generated by a
rhythmogenic interplay between the cortex and the thalamus. However, the question …

[HTML][HTML] The role of thalamic nuclei in genetic generalized epilepsies

A Lüttjohann, G van Luijtelaar - Epilepsy research, 2022 - Elsevier
There is no doubt on the participation of the thalamus in the various types of genetic
generalized epilepsies as evidenced by multiple non-invasive imaging studies in humans as …

IL-1β is induced in reactive astrocytes in the somatosensory cortex of rats with genetic absence epilepsy at the onset of spike-and-wave discharges, and contributes to …

D Akin, T Ravizza, M Maroso, N Carcak, T Eryigit… - Neurobiology of …, 2011 - Elsevier
Interleukin (IL)-1β plays a crucial role in the mechanisms of limbic seizures in rodent models
of temporal lobe epilepsy. We addressed whether activation of the IL-1β signaling occurs in …

Seizure expression, behavior, and brain morphology differences in colonies of Genetic Absence Epilepsy Rats from Strasbourg

KL Powell, H Tang, C Ng, I Guillemain, G Dieuset… - …, 2014 - Wiley Online Library
Objective Originally derived from a Wistar rat strain, a proportion of which displayed
spontaneous absence‐type seizures, Genetic Absence Epilepsy Rats from Strasbourg …

Building up absence seizures in the somatosensory cortex: from network to cellular epileptogenic processes

G Jarre, T Altwegg-Boussac, MS Williams… - Cerebral …, 2017 - academic.oup.com
The epileptogenic processes leading to recurrent seizures in Genetic Epilepsies are largely
unknown. Using the Genetic Absence Epilepsy Rat from Strasbourg, we investigated in vivo …

Recognizing of stereotypic patterns in epileptic EEG using empirical modes and wavelets

VV Grubov, E Sitnikova, AN Pavlov… - Physica A: Statistical …, 2017 - Elsevier
Epileptic activity in the form of spike–wave discharges (SWD) appears in the
electroencephalogram (EEG) during absence seizures. This paper evaluates two …

Modulation of pacemaker channel function in a model of thalamocortical hyperexcitability by demyelination and cytokines

R Chaudhary, S Albrecht, M Datunashvili… - Cerebral …, 2022 - academic.oup.com
A consensus is yet to be reached regarding the exact prevalence of epileptic seizures or
epilepsy in multiple sclerosis (MS). In addition, the underlying pathophysiological basis of …

Neonatal sensory deprivation promotes development of absence seizures in adult rats with genetic predisposition to epilepsy

E Sitnikova - Brain research, 2011 - Elsevier
Absence epilepsy has age-related onset. In a WAG/Rij rat genetic model, absence seizures
appear after puberty and they are increased with age. It is known that (1) epileptic activity in …

Relationships between astrocytes and absence epilepsy in rat: an experimental study

S Çavdar, Y Kuvvet, I Sur-Erdem, M Özgür, F Onat - Neuroscience letters, 2019 - Elsevier
Astrocytes take part in the modulation of neuronal activity through the uptake and release of
both GABA and glutamate. In the present study we aimed to quantify the number of …

Age‐dependent increase of absence seizures and intrinsic frequency dynamics of sleep spindles in rats

E Sitnikova, AE Hramov, V Grubov… - Neuroscience …, 2014 - Wiley Online Library
The risk of neurological diseases increases with age. In WAG/Rij rat model of absence
epilepsy, the incidence of epileptic spike‐wave discharges is known to be elevated with age …