Immunosuppressive medications are widely used to treat patients with neoplasms,
autoimmune conditions and solid organ transplants. Key drug classes, namely calcineurin …

Background Successful maintenance of a heart transplant (HTx) graft requires adherence to
a triple-drug regimen of immunosuppression. However, achieving adequate adherence can …

Cardiovascular disease is one of the main diseases that endanger human life and health,
and heart failure often occurs when the cardiovascular disease develops to the end-stage …

Background Acute kidney injury (AKI) commonly occurs after heart transplantation (HTx), but
its association with preoperative right ventricular (RV) function remains unknown …

Heart transplantation (HT) remains the best treatment of patients with severe heart failure
who are deemed to be transplant candidates. In 2022, 3620 adults underwent HT in the …

Background: Dendritic cells (DCs) serve as an important part of the immune system and play
a dual role in immune response. Mature DCs can initiate immune response, while immature …

Apixaban and dabigatran are the two major direct oral anticoagulant drugs to treat
thromboembolic disordered patients. Increasing the clinical application for the …

Matrine, an alkaloid derived from traditional Chinese herbs, has been confirmed to regulate
immunity and exert anti-inflammatory effects. Matrine injection has been widely used in clinic …

Heart transplantation is a definitive treatment option for patients with end‐stage heart failure.
Medical and functional complications are common after this procedure, and rehabilitation is …

Introduction Pediatric heart transplant patients are routinely followed in dermatology clinics
due to elevated risk of cutaneous malignancy. However, transplant patients may experience …