An in-depth review: Unraveling the extraction, structure, bio-functionalities, target molecules, and applications of pectic polysaccharides
Y Pang, Z Peng, K Ding - Carbohydrate Polymers, 2024 - Elsevier
Pectic polysaccharides have long been a challenging subject of research in the field of
macromolecular science, given their complex structures and wide range of biological effects …
macromolecular science, given their complex structures and wide range of biological effects …
Decoding the immune dance: Unraveling the interplay between beta cells and type 1 diabetes
S Roy, P Pokharel, JD Piganelli - Molecular Metabolism, 2024 - Elsevier
Abstract Background Type 1 diabetes (T1D) is an autoimmune disease characterized by the
specific destruction of insulin-producing beta cells in the pancreas by the immune system …
specific destruction of insulin-producing beta cells in the pancreas by the immune system …
[HTML][HTML] The Dual Burden: Exploring Cardiovascular Complications in Chronic Kidney Disease
A Caturano, R Galiero, M Rocco, G Tagliaferri… - Biomolecules, 2024 - mdpi.com
Chronic kidney disease (CKD) represents a significant global health challenge, affecting
millions of individuals and leading to substantial morbidity and mortality. This review aims to …
millions of individuals and leading to substantial morbidity and mortality. This review aims to …
Engineered vildagliptin-loaded polymeric nanoparticles via microfluidic and spray drying for enhanced antidiabetic activity
Background Vildagliptin (VLG), an antidiabetic agent, presents a potential solution to this
widespread affliction. It exhibits notable attributes, such as a high solubility and a shorter …
widespread affliction. It exhibits notable attributes, such as a high solubility and a shorter …
Recent Advances in the Development of Alpha-Glucosidase and Alpha-Amylase Inhibitors in Type 2 Diabetes Management: Insights from In silico to In vitro Studies
Diabetes is a metabolic disorder caused by high glucose levels, leading to serious threats
such as diabetic neuropathy and cardiovascular diseases. One of the most reliable …
such as diabetic neuropathy and cardiovascular diseases. One of the most reliable …
The potential mechanism of remission in type 2 diabetes mellitus after vertical sleeve gastrectomy
R Wang, S Mijiti, Q Xu, Y Liu, C Deng, J Huang… - Obesity Surgery, 2024 - Springer
In recent years, there has been a gradual increase in the prevalence of obesity and type 2
diabetes mellitus (T2DM), with bariatric surgery remaining the most effective treatment …
diabetes mellitus (T2DM), with bariatric surgery remaining the most effective treatment …
Benzothiazole derivatives as effective α-glucosidase inhibitors: an insight study of structure-activity relationships and molecular targets
Z Khalifa, R Upadhyay, AB Patel - Medicinal Chemistry Research, 2024 - Springer
In treating the major metabolic disorder diabetes mellitus type-2, the α-glucosidase enzyme
inhibitors play an effective role due to their vital capability of polysaccharide hydrolyzation. A …
inhibitors play an effective role due to their vital capability of polysaccharide hydrolyzation. A …
Novel insights into the activating transcription factor 4 in Alzheimer's disease and associated aging-related diseases: Mechanisms and therapeutic implications
N Zhang, J Nao, S Zhang, X Dong - Frontiers in Neuroendocrinology, 2024 - Elsevier
Ageing is inherent to all human beings, most mechanistic explanations of ageing results
from the combined effects of various physiological and pathological processes. Additionally …
from the combined effects of various physiological and pathological processes. Additionally …
Unveiling the Chemistry of Citrus Peel: Insights into Nutraceutical Potential and Therapeutic Applications
The recent millennium has witnessed a notable shift in consumer focus towards natural
products for addressing lifestyle-related disorders, driven by their safety and cost …
products for addressing lifestyle-related disorders, driven by their safety and cost …
Assessment of new-onset heart failure prediction in a diabetic population using left ventricular global strain: a prospective cohort study based on UK Biobank
S Chen, C Chen, L Zheng, W Cheng, X Bu… - Frontiers in …, 2024 - frontiersin.org
Background Impaired glucose utilization influences myocardial contractile function.
However, the prognostic importance of left ventricular global radial strain (LV-GRS), left …
However, the prognostic importance of left ventricular global radial strain (LV-GRS), left …