Regulation mechanisms of viral IRES-driven translation

KM Lee, CJ Chen, SR Shih - Trends in microbiology, 2017 - cell.com
Internal ribosome entry sites (IRESs) can be found in the mRNA of many viruses as well as
in cellular genes involved in the stress response, cell cycle, and apoptosis. IRES-mediated …

Regulation of ribosomal proteins on viral infection

S Li - Cells, 2019 - mdpi.com
Ribosomal proteins (RPs), in conjunction with rRNA, are major components of ribosomes
involved in the cellular process of protein biosynthesis, known as “translation”. The viruses …

[PDF][PDF] Structured elements drive extensive circular RNA translation

CK Chen, R Cheng, J Demeter, J Chen… - Molecular cell, 2021 - cell.com
The human genome encodes tens of thousands circular RNAs (circRNAs) with mostly
unknown functions. Circular RNAs require internal ribosome entry sites (IRES) if they are to …

Viral internal ribosomal entry sites: four classes for one goal

J Mailliot, F Martin - Wiley Interdisciplinary Reviews: RNA, 2018 - Wiley Online Library
To ensure efficient propagation, viruses need to rapidly produce viral proteins after cell
entrance. Since viral genomes do not encode any components of the protein biosynthesis …

Does functional specialization of ribosomes really exist?

MB Ferretti, K Karbstein - Rna, 2019 - rnajournal.cshlp.org
It has recently become clear that ribosomes are much more heterogeneous than previously
thought, with diversity arising from rRNA sequence and modifications, ribosomal protein …

Identification of COVID-19 prognostic markers and therapeutic targets through meta-analysis and validation of Omics data from nasopharyngeal samples

A Biji, O Khatun, S Swaraj, R Narayan, RS Rajmani… - …, 2021 - thelancet.com
Background While our battle with the COVID-19 pandemic continues, a multitude of Omics
data have been generated from patient samples in various studies. Translation of these data …

Molecular architecture of the ribosome‐bound Hepatitis C Virus internal ribosomal entry site RNA

H Yamamoto, M Collier, J Loerke, J Ismer… - The EMBO …, 2015 - embopress.org
Internal ribosomal entry sites (IRES s) are structured cis‐acting RNA s that drive an
alternative, cap‐independent translation initiation pathway. They are used by many viruses …

Selective regulation in ribosome biogenesis and protein production for efficient viral translation

HJ Dong, R Zhang, Y Kuang, XJ Wang - Archives of Microbiology, 2021 - Springer
As intracellular parasites, viruses depend heavily on host cell structures and their functions
to complete their life cycle and produce new viral particles. Viruses utilize or modulate …

[HTML][HTML] Ribosomal protein L13 participates in innate immune response induced by foot-and-mouth disease virus

J Guan, S Han, J Wu, Y Zhang, M Bai… - Frontiers in …, 2021 - frontiersin.org
In addition to ribosomal protein synthesis and protein translation, ribosomal proteins also
participate in tumorigenesis and tumor progression, immune responses, and viral …

Large-scale population structure and genetic architecture of agronomic traits of garlic

H Jia, Q Zhao, J Song, X Zhang, W Yang… - Horticulture …, 2023 - academic.oup.com
Garlic, an asexually propagated crop, is the second important bulb crop after the onion and
is used as a vegetable and medicinal plant. Abundant and diverse garlic resources have …