The complement system comprises several fluid-phase and membrane-associated proteins.
Under physiological conditions, activation of the fluid-phase components of complement is …

The complement system was discovered a century ago as a potent defense cascade of
innate immunity. After its first description, continuous experimental and clinical research was …

The human collectin, mannose‐binding lectin (MBL), is an important protein of the humoral
innate immune system. With multiple carbohydrate‐recognition domains, it is able to bind to …

A major function of the immune system is to protect the host from microbial infections. The
complement system plays important roles in both the innate and the adaptive immune …

Mannan-binding lectin (MBL) deficiency has been classified as a commonly occurring
immune disorder, affecting approximately 30% of the human population. MBL, being part of …

The innate host defence molecule mannose‐binding lectin (MBL) has attracted great interest
as a potential candidate for passive immunotherapy to prevent infection. MBL is a multimeric …

Mannose-binding lectin (MBL) is a recognition molecule of the lectin pathway of complement
and a key component of innate immunity. MBL variant alleles have been described in the …

Background. Previous studies have shown associations between low mannose-binding
lectin (MBL) level or variant MBL2 genotype and sepsis susceptibility. However, MBL …

Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the
ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More …

The ability of a pathogen to evade host immunity successfully, in contrast to the host's
capacity to defend itself against a foreign invader, is a complex struggle, in which …