Ultraviolet photodissociation (UVPD) has been shown to be a versatile ion activation
strategy for the characterization of peptides and intact proteins among other classes of …

Capillary vibrating sharp-edge spray ionization (cVSSI) has been used to control the droplet
charging of nebulized microdroplets and monitor effects on protein ion conformation makeup …

Mass-spectrometry based assays in structural biology studies measure either intact or
digested proteins. Typically, different mass spectrometers are dedicated for such …

Collision-induced unfolding (CIU) has provided new levels of understanding of the stabilities
and structure (s) for gas phase protein and protein complex ions formed by electrospray …

Investigating the structural heterogeneity of monoclonal antibodies is crucial to achieving
optimal therapeutic outcomes. We show that tandem-trapped ion mobility spectrometry …