The human gut microbiome is a dynamic collection of bacteria, archaea, fungi, and viruses
that performs essential functions for immune development, pathogen colonization …

Background Antibiotics are used frequently in the neonatal intensive care unit. We aimed to
inform antibiotic stewardship strategies in a level 3 neonatal intensive care unit by …

Background Global assessment of antimicrobial agents prescribed to infants in the neonatal
intensive care unit (NICU) may inform antimicrobial stewardship efforts. Methods We …

Objectives: We aimed to implement our Smart Use of Antibiotics Program to ensure the
proper use of antimicrobials, improve patient care and outcomes, and reduce the risks of …

Antibiotic stewardship is a multidisciplinary, evidence-based approach to optimize antibiotic
use and mitigate development of antibiotic resistance. Neonates have high rates of antibiotic …

Antibiotics are invaluable in the management of neonatal infections. However, overuse or
misuse of antibiotics in neonates has been associated with adverse outcomes, including …

Background Prolonged or unnecessary antibiotic use is associated with adverse outcomes
in infants. Antibiotic stewardship programs (ASPs) aim to prevent these adverse outcomes …

Objectives: To observe the duration for normalization of the Total Leucocyte Count (TLC)
with adjuvant Granulocyte-Colony Stimulating Factor (G-CSF) treatment in leukopenic …

METHODS Remote ASP was implemented in 8 medically underserved newborn nurseries
using a stepped-wedge, cluster-randomized design over 3 years. This included a 15-month …

Background: Neonatal sepsis is a clinical syndrome of bacteremia with systemic signs and is
the most important cause of neonatal death in developing country. Mortality increase with …