Synthetic biopolymers are effective cues to replace damaged tissue in the tissue
engineering (TE) field, both for in vitro and in vivo application. Among them, poly-l-lactic acid …

Bone tissue engineering has emerged as a promising strategy to overcome the limitations of
current treatments for bone-related disorders, but the trade-off between mechanical …

Bone scaffolds play an important role in promoting the healing of large bone defects.
However, the type of scaffold material, type of drug loaded into the scaffold, and method of …

Nanohydroxyapatite (nanoHA) is the major mineral component of bone. It is highly
biocompatible, osteoconductive, and forms strong bonds with native bone, making it an …

In this study, polylactic acid (PLA) was reinforced with hydroxyapatite (HAp) microparticles
and strontium (Sr) powder via the melt extrusion/hot pressing manufacturing process to …

The occurrence of periprosthetic femoral fractures (PFF) has increased in people with
osteoporosis due to decreased bone density, poor bone quality, and stress shielding from …

The use of biomaterials and scaffolds to boost bone regeneration is increasingly gaining
interest as a complementary method to the standard surgical and pharmacological …

The in vitro evaluation of 3D scaffolds for bone tissue engineering in mono-cultures is a
common practice; however, it does not represent the native complex nature of bone tissue …

Bone defects in animals can arise from various causes, including diseases, neoplasms, and
most commonly, trauma. Comminuted fractures that exceed the critical size may heal poorly …

The present work evaluates chitosan/sodium alginate blended with two nanomaterials of
hydroxyapatite (HA) and commercial nanoclay-Cloisite20A for improving bone regeneration …