An assessment on impact of COVID-19 infection in a gender specific manner

H Agrawal, N Das, S Nathani, S Saha, S Saini… - Stem cell reviews and …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by novel coronavirus Severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It was first time reported in …

Regulation and directing stem cell fate by tissue engineering functional microenvironments: scaffold physical and chemical cues

F Xing, L Li, C Zhou, C Long, L Wu, H Lei… - Stem cells …, 2019 - Wiley Online Library
It is well known that stem cells reside within tissue engineering functional
microenvironments that physically localize them and direct their stem cell fate. Recent efforts …

Asthma: the use of animal models and their translational utility

JS Woodrow, MK Sheats, B Cooper, R Bayless - Cells, 2023 - mdpi.com
Asthma is characterized by chronic lower airway inflammation that results in airway
remodeling, which can lead to a permanent decrease in lung function. The pathophysiology …

Treatment of cystic fibrosis: from gene-to cell-based therapies

KM Allan, N Farrow, M Donnelley, A Jaffe… - Frontiers in …, 2021 - frontiersin.org
Prognosis of patients with cystic fibrosis (CF) varies extensively despite recent advances in
targeted therapies that improve CF transmembrane conductance regulator (CFTR) function …

Immunomodulatory properties of mesenchymal stem cells: A potential therapeutic strategy for allergic rhinitis

M Wang, N Zhao, C Wang, ZB Jin, L Zhang - Allergy, 2023 - Wiley Online Library
Allergic rhinitis is a highly prevalent chronic inflammatory disorder of the nasal mucosa that
poses a significant burden on patients' health and quality of life. Current therapies for …

Mesenchymal stromal cells: an antimicrobial and host-directed therapy for complex infectious diseases

TD Shaw, AD Krasnodembskaya… - Clinical microbiology …, 2021 - Am Soc Microbiol
There is an urgent need for new antimicrobial strategies for treating complex infections and
emerging pathogens. Human mesenchymal stromal cells (MSCs) are adult multipotent cells …

State of the art review of cell therapy in the treatment of lung disease, and the potential for aerosol delivery

H Brave, R MacLoughlin - International Journal of Molecular Sciences, 2020 - mdpi.com
Respiratory and pulmonary diseases are among the leading causes of death globally.
Despite tremendous advancements, there are no effective pharmacological therapies …

[HTML][HTML] Imaging drug delivery to the lungs: Methods and applications in oncology

F Man, J Tang, M Swedrowska, B Forbes… - Advanced Drug Delivery …, 2023 - Elsevier
Direct delivery to the lung via inhalation is arguably one of the most logical approaches to
treat lung cancer using drugs. However, despite significant efforts and investment in this …

Targeting the angiopoietin/tie pathway: prospects for treatment of retinal and respiratory disorders

RG Akwii, CM Mikelis - Drugs, 2021 - Springer
Anti-angiogenic approaches have significantly advanced the treatment of vascular-related
pathologies. The ephemeral outcome and known side effects of the current vascular …

Therapeutic potential of mesenchymal stem cells and their products in lung diseases—intravenous administration versus inhalation

E Fröhlich - Pharmaceutics, 2021 - mdpi.com
The number of publications studying the therapeutic use of stem cells has steadily increased
since 2000. Compared to other applications, there has been little interest in the evaluation of …