The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

The introduction of the in vitro evolution method known as SELEX (systematic evolution of
ligands by exponential enrichment) more than 30 years ago led to the conception of …

Aptamers are short single-stranded nucleic acid sequences capable of binding to target
molecules in a way similar to antibodies. Due to various advantages such as prolonged …

Aptamers have been identified against various targets as a type of chemical or nucleic acid
ligand by systematic evolution of ligands by exponential enrichment (SELEX) with high …

Nowadays, there is a high demand for sensitive and selective real-time analytical methods
suitable for a wide range of applications, from personalized telemedicine, drug discovery …

Aptamers play an important role in biomedical industry due to their great affinity to bind to
target site. Due to their targeting potency, an adequate amount of therapeutically active drug …

It has been almost 30 years since the invention of Systematic Evolution of Ligands by
Exponential Enrichment (SELEX) methodology and the description of the first aptamers. In …

Conventional anticancer therapies, such as chemo-and/or radio-therapy are often unable to
completely eradicate cancers due to abnormal tumor microenvironment, as well as …

Lateral flow assay (LFA) has made a paradigm shift in the in vitro diagnosis field due to its
rapid turnaround time, ease of operation and exceptional affordability. Currently used LFAs …

The mainstay of clinical diagnostics is the use of specialised ligands that can recognise
specific biomarkers relating to pathological changes. While protein antibodies have been …