Chronic lung disease determines the morbidity and mortality of cystic fibrosis (CF) patients.
The pulmonary immune response in CF is characterized by an early and non-resolving …

The role of neutrophils in cystic fibrosis : Current Opinion in Hematology The role of neutrophils in
cystic fibrosis : Current Opinion in Hematology Log in or Register Subscribe to journalSubscribe …

Neutrophils are highly specialized innate immune effector cells that evolved for antimicrobial
host defense. In response to inflammatory stimuli and pathogens, they form neutrophil …

The inability of neutrophils to eradicate Pseudomonas aeruginosa within the cystic fibrosis
(CF) airway eventually results in chronic infection by the bacteria in nearly 80 percent of …

Studies have endeavored to reconcile whether dysfunction of neutrophils in people with
cystic fibrosis (CF) is a result of the genetic defect or is secondary due to infection and …

Cystic fibrosis (CF), the most common lethal single-gene disorder affecting Northern
Europeans and North Americans, is caused by mutations in the cystic fibrosis …

Optimal microbicidal activity of human polymorphonuclear leukocytes (PMN) relies on the
generation of toxic agents such as hypochlorous acid (HOCl) in phagosomes. HOCl …

Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen with multiple niches in the
human body, including the lung. P. aeruginosa infections are particularly damaging or fatal …

Cystic fibrosis (CF), caused by mutations in the cystic fibrosis transmembrane conductance
regulator (CFTR) gene, is the most common inherited life-limiting disease in North European …

Studies have endeavored to understand the cause for impaired antimicrobial killing by
neutrophils of people with cystic fibrosis (PWCF). The aim of this study was to focus on the …