Tumorigenesis in inflammatory bowel disease: microbiota-environment interconnections

I Mignini, ME Ainora, S Di Francesco, L Galasso… - Cancers, 2023 - mdpi.com
Simple Summary The role of gut microbiota and environmental factors on IBD-related CRC
is still a burning question. Crohn's Disease (CD) and Ulcerative Colitis (UC) are complex …

The lung microbiome in COPD and lung cancer: Exploring the potential of metal-based drugs

M O'Shaughnessy, O Sheils, AM Baird - International Journal of …, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) and lung cancer 17 are two of the most
prevalent and debilitating respiratory diseases worldwide, both associated with high …

[HTML][HTML] Role of circular RNAs and gut microbiome in gastrointestinal cancers and therapeutic targets

ST Abdullah, SR Abdullah, BM Hussen… - Non-coding RNA …, 2023 - Elsevier
Gastrointestinal cancers are a huge worldwide health concern, which includes a wide
variety of digestive tract cancers. Circular RNAs (circRNAs), a kind of non-coding RNA …

Association between surrogate markers of insulin resistance and the incidence of colorectal cancer in Korea: A nationwide population-based study

M Son, SY Moon, M Koh, Y Kang, JY Lee - Journal of Clinical Medicine, 2024 - mdpi.com
Background: Insulin resistance (IR) is assessed using surrogate markers such as the
triglyceride–glucose (TyG) index, the triglyceride-to-high-density lipoprotein cholesterol …

VAX014, an Oncolytic Therapy, Reduces Adenomas and Modifies Colon Microenvironment in Mouse Model of CRC

SF Grenier, MW Khan, KA Reil, S Sawaged… - International Journal of …, 2023 - mdpi.com
Colorectal cancer (CRC) remains the third most common form of cancer and, despite its
reduced mortality, results in over 50,000 deaths annually, highlighting the need for novel …

Functional effects of yacon (Smallanthus sonchifolius) and kefir on systemic inflammation, antioxidant activity, and intestinal microbiome in rats with induced colorectal …

KR Zanardi, M Grancieri, CW Silva, LO Trivillin… - Food & Function, 2023 - pubs.rsc.org
Colorectal cancer (CRC) is one of the most common cancers with high morbidity and
mortality. The modulation of intestinal health through the administration of pro-and prebiotics …

[HTML][HTML] Obesity under the moonlight of c-MYC

YA Nevzorova, FJ Cubero - Frontiers in Cell and Developmental …, 2023 - ncbi.nlm.nih.gov
The moonlighting protein c-Myc is a master regulator of multiple biological processes
including cell proliferation, differentiation, angiogenesis, apoptosis and metabolism. It is …

The Complex Connection between Obesity and Cancer: Signaling Pathways and Therapeutic Implications

M El-Tanani, SA Rabbani, AA Aljabali… - Nutrition and …, 2024 - Taylor & Francis
Obesity has emerged as an important global health challenge, significantly influencing the
incidence and progression of various cancers. This comprehensive review elucidates the …

Exploring the Potential Protective Effect of Probiotics in Obesity-Induced Colorectal Cancer: What Insights Can In Vitro Models Provide?

R Viana, AC Rocha, AP Sousa, D Ferreira… - Applied Sciences, 2024 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer diagnosed today and the third
leading cause of death among cancer types. CRC is one of the gastrointestinal tumors with …

Role of Gut Microbiota in Predisposition to Colon Cancer: A Narrative Review

HS Kamath, R Shukla, U Shah, S Patel, S Das… - Indian Journal of …, 2024 - Springer
Globally, colorectal cancer (CRC) is a leading cause of cancer-related mortality. Dietary
habits, inflammation, hereditary characteristics, and gut microbiota are some of its causes …