Grains–a major source of sustainable protein for health

KS Poutanen, AO Kårlund, C Gómez-Gallego… - Nutrition …, 2022 - academic.oup.com
Cereal grains are the main dietary source of energy, carbohydrates, and plant proteins world-
wide. Currently, only 41% of grains are used for human consumption, and up to 35% are …

Pathogenesis of celiac disease and other gluten related disorders in wheat and strategies for mitigating them

N Sharma, S Bhatia, V Chunduri, S Kaur… - Frontiers in …, 2020 - frontiersin.org
Wheat is a major cereal crop providing energy and nutrients to the billions of people around
the world. Gluten is a structural protein in wheat, that is necessary for its dough making …

Next-generation therapies for celiac disease: The gluten-targeted approaches

M Ribeiro, FM Nunes, M Rodriguez-Quijano… - Trends in Food Science …, 2018 - Elsevier
Background Wheat is one of the main foods of the human diet. It contains a protein complex,
gluten, which is primarily responsible for the rheological behavior of wheat flours. However …

Review of structural features and binding capacity of polyphenols to gluten proteins and peptides in vitro: Relevance to celiac disease

M Ribeiro, T Sousa, P Poeta, AS Bagulho, G Igrejas - Antioxidants, 2020 - mdpi.com
Polyphenols have been extensively studied due to their beneficial effects on human health,
particularly for the prevention and treatment of diseases related to oxidative stress …

A review of gluten detoxification in wheat for food applications: approaches, mechanisms, and implications

Y Zhang, H Wu, L Fu - Critical Reviews in Food Science and …, 2024 - Taylor & Francis
With the improved knowledge of gluten-related disorders, especially celiac disease (CD),
the market of gluten-free food is growing. However, the current gluten-free diet still presents …

IDP Force Fields Applied to Model PPII-Rich 33-mer Gliadin Peptides

MJ Amundarain, A Vietri, VI Dodero… - The Journal of …, 2023 - ACS Publications
The 33-mer gliadin peptide and its deamidated metabolite, 33-mer DGP, are the
immunodominant peptides responsible for the adaptive immune response in celiac disease …

Development of celiac-safe foods: prevention of transglutaminase 2 (TG2) deamidation of gluten in healthy non-celiac volunteers

N Engström, L Böhn, A Josefsson, S Störsrud… - Frontiers in …, 2024 - frontiersin.org
In celiac disease, intestinal transglutaminase (TG2) produces immunogenic peptides by
deamidation of gluten proteins. These products drive the celiac immune response. We have …

Health hazards associated with wheat and gluten consumption in susceptible individuals and status of research on dietary therapies

S Rustgi, P Shewry, F Brouns - Wheat Quality For Improving Processing …, 2020 - Springer
Wheat accounts for about 20% to over 50% of the total calorie intake of food in regions
where it is grown. However, there is a clear perception that disorders related to the …

The Diverse Potential of Gluten from Different Durum Wheat Varieties in Triggering Celiac Disease: A Multilevel In Vitro, Ex Vivo and In Vivo Approach

F Gaiani, S Graziano, F Boukid, B Prandi, L Bottarelli… - Nutrients, 2020 - mdpi.com
The reasons behind the increasing prevalence of celiac disease (CD) worldwide are still not
fully understood. This study adopted a multilevel approach (in vitro, ex vivo, in vivo) to …

[PDF][PDF] Development of celiac-safe

N Engström, L Böhn, A Josefsson, S Störsrud… - 2024 - research.chalmers.se
Celiac disease (gluten intolerance) is an HLA-linked inflammatory autoimmune condition
that primarily affects the small intestine. The classical symptoms are pain, diarrhea, and …