Advances in biomaterials and technologies for vascular embolization

J Hu, H Albadawi, BW Chong, AR Deipolyi… - Advanced …, 2019 - Wiley Online Library
Minimally invasive transcatheter embolization is a common nonsurgical procedure in
interventional radiology used for the deliberate occlusion of blood vessels for the treatment …

Innovative design of targeted nanoparticles: polymer–drug conjugates for enhanced cancer therapy

VB Junyaprasert, P Thummarati - Pharmaceutics, 2023 - mdpi.com
Polymer–drug conjugates (PDCs) have shown great promise in enhancing the efficacy and
safety of cancer therapy. These conjugates combine the advantageous properties of both …

Drug-encapsulated blend of PLGA-PEG microspheres: in vitro and in vivo study of the effects of localized/targeted drug delivery on the treatment of triple-negative …

SM Jusu, JD Obayemi, AA Salifu, CC Nwazojie… - Scientific Reports, 2020 - nature.com
Triple-negative breast cancer (TNBC) is more aggressive and difficult to treat using
conventional bulk chemotherapy that is often associated with increased toxicity and side …

[HTML][HTML] Receptor-mediated targeted delivery of surface-ModifiedNanomedicine in breast cancer: Recent update and challenges

M Rizwanullah, MZ Ahmad, MM Ghoneim, S Alshehri… - Pharmaceutics, 2021 - mdpi.com
Breast cancer therapeutic intervention continues to be ambiguous owing to the lack of
strategies for targeted transport and receptor-mediated uptake of drugs by cancer cells. In …

Conventional and new proposals of GnRH therapy for ovarian, breast, and prostatic cancers

MP Garrido, A Hernandez, M Vega, E Araya… - Frontiers in …, 2023 - frontiersin.org
For many years, luteinizing hormone-releasing hormone or gonadotropin-releasing
hormone (GnRH) analogs have been used to treat androgen or estrogen-dependent tumors …

Magnetite nanoparticles coated with PEG 3350-Tween 80: In vitro characterization using primary cell cultures

JA Roacho-Pérez, FG Ruiz-Hernandez… - Polymers, 2020 - mdpi.com
Some medical applications of magnetic nanoparticles require direct contact with healthy
tissues and blood. If nanoparticles are not designed properly, they can cause several …

A review on targeting nanoparticles for breast cancer

HGJ Alqaraghuli, S Kashanian… - Current pharmaceutical …, 2019 - ingentaconnect.com
Chemotherapeutic agents have been used extensively in breast cancer remedy. However,
most anticancer drugs cannot differentiate between cancer cells and normal cells, leading to …

Triptorelin-functionalized PEG-coated biosynthesized gold nanoparticles: Effects of receptor-ligand interactions on adhesion to triple negative breast cancer cells

VO Uzonwanne, A Navabi, JD Obayemi, J Hu… - Biomaterials …, 2022 - Elsevier
This paper presents the results of an experimental and computational study of the adhesion
of triptorelin-conjugated PEG-coated biosynthesized gold nanoparticles (GNP-PEG-TRP) to …

New drug delivery strategies targeting the GnRH receptor in breast and other cancers

HSA Ghaly, P Varamini - Endocrine-Related Cancer, 2021 - erc.bioscientifica.com
Cancer is the uncontrolled division of abnormal cells in a specific organ. Globally, about one
in six deaths is due to cancer. Despite the plethora of research being undertaken worldwide …

Super-paramagnetic magnetite nanoparticles obtained by different synthesis and separation methods stabilized by biocompatible coatings

AJ Szalai, N Manivannan, G Kaptay - Colloids and Surfaces A …, 2019 - Elsevier
Magnetite nanoparticles were chemically synthesized by co-precipitation method, using
gelatine added in-situ and ex-situ and also using two different separation techniques for the …