Pectin-like polysaccharide extracted from the leaves of Conocarpus erectus Linnaeus promotes antioxidant, immunomodulatory and prebiotic effects
DKD do Nascimento Santos, BR da Silva Barros… - … and Dietary Fibre, 2021 - Elsevier
Pectins are complex heteropolysaccharides made up of a linear main chain of repeated
units of galacturonic acid that can promote different biological activities. This work aimed to …
units of galacturonic acid that can promote different biological activities. This work aimed to …
[HTML][HTML] Immunostimulatory and antioxidant activities of a lignin isolated from Conocarpus erectus leaves
DKD do Nascimento Santos, BR da Silva Barros… - International journal of …, 2020 - Elsevier
In this work, we investigated the antioxidant and immunomodulatory activities of a lignin
isolated from Conocarpus erectus leaves. The lignin was characterized by FTIR, 1 H NMR …
isolated from Conocarpus erectus leaves. The lignin was characterized by FTIR, 1 H NMR …
Antigen-drug conjugates as a novel therapeutic class for the treatment of antigen-specific autoimmune disorders
CJ Pickens, MA Christopher, MA Leon… - Molecular …, 2019 - ACS Publications
Multiple sclerosis represents the world's most common cause of neurological disability in
young people and is attributed to a loss of immune tolerance toward proteins of the myelin …
young people and is attributed to a loss of immune tolerance toward proteins of the myelin …
Co-delivery of autoantigen and dexamethasone in incomplete Freund's adjuvant ameliorates experimental autoimmune encephalomyelitis
L Northrup, JD Griffin, MA Christopher… - Journal of Controlled …, 2017 - Elsevier
Current therapies for autoimmune diseases focus on treating the symptoms rather than the
underlying disease cause. A major setback in improving current therapeutics for …
underlying disease cause. A major setback in improving current therapeutics for …
Controlled release of second generation mTOR inhibitors to restrain inflammation in primary immune cells
EA Gosselin, LH Tostanoski, CM Jewell - The AAPS Journal, 2017 - Springer
Autoimmune disease occurs when the immune system incorrectly targets the body's own
tissue. Inflammatory CD4+ T cell phenotypes, such as TH 1 and TH 17, are key drivers of this …
tissue. Inflammatory CD4+ T cell phenotypes, such as TH 1 and TH 17, are key drivers of this …
Complete Tolerogenic Adjuvant Stimulates Regulatory T Cell Response to Immunization
We have determined in mice the minimum composition required for forming a vaccine
adjuvant that stimulates a regulatory T (Treg) cell response to immunization, and we named …
adjuvant that stimulates a regulatory T (Treg) cell response to immunization, and we named …