Myelin debris phagocytosis in demyelinating disease

R Gao, SJ Song, MY Tian, LB Wang, Y Zhang, X Li - Glia, 2024 - Wiley Online Library
Demyelinating diseases are often caused by a variety of triggers, including immune
responses, viral infections, malnutrition, hypoxia, or genetic factors, all of which result in the …

[HTML][HTML] PPARs in atherosclerosis: The spatial and temporal features from mechanism to druggable targets

Y Zheng, M Shao, Y Zheng, W Sun, S Qin, Z Sun… - Journal of Advanced …, 2024 - Elsevier
Background Atherosclerosis is a chronic and complex disease caused by lipid disorder,
inflammation, and other factors. It is closely related to cardiovascular diseases, the chief …

Multi-effective nanoplatform with down/upconversion dual-mode emissions for NIR-II imaging and PDT/PTT synergistic therapy of early atherosclerosis

W Gao, L Lv, G Li, H Zhao, J Zhou, Y Cheng… - Chemical …, 2024 - pubs.rsc.org
We design a multi-effective nanoplatform (CeO2: Nd@ SiO2@ CeO2: Yb, Er@ SiO2-
RB/MB/CD36) with down/upconversion dual-mode emissions and targeting ability in foam …

Oridonin attenuates liver ischemia–reperfusion injury by suppressing PKM2/NLRP3-mediated macrophage pyroptosis

X Wu, M Zhao, W Liao, T Liu, JY Liu, J Gong, X Lai… - Cellular …, 2024 - Elsevier
Background The NOD-like receptor protein 3 (NLRP3) mediated pyroptosis of macrophages
is closely associated with liver ischemia reperfusion injury (IRI). As a covalent inhibitor of …

FABP4 Inhibitor Alleviates Lipopolysaccharide-Induced HUVEC Injury by Inactivating NF-κB and Activating PPARγ

S Sun, X Duan, Q Wu, X Bu, Y He, X Ming… - International Heart …, 2024 - jstage.jst.go.jp
The study aims to examine the effect of FABP4 on inflammatory response and angiogenesis
in the cell model of atherosclerosis and to explore its potential mechanism. Using reverse …