The intestinal microbiome influences host health, and its responsiveness to diet and disease
is increasingly well studied. However, our understanding of the factors driving microbiome …

Many bacterial species in nature possess the ability to transition into a sessile lifestyle and
aggregate into cohesive colonies, known as biofilms. Within a biofilm, bacterial cells are …

Bacterial antimicrobial resistance (AMR) is among the most significant challenges to current
human society. Exposing bacteria to antibiotics can activate their self-saving responses, eg …

Inside prokaryotic cells, passive translational diffusion typically limits the rates with which
cytoplasmic proteins can reach their locations. Diffusion is thus fundamental to most cellular …

The widespread bacterial second messenger c-di-GMP is responsible for regulating many
important physiological functions such as biofilm formation, motility, cell differentiation, and …

Cyclic diguanylate (c-di-GMP) signal transduction systems provide bacteria with the ability to
sense changing cell status or environmental conditions and then execute suitable …

In natural environments, bacteria constantly encounter various stressful conditions, including
nutrient starvation, toxic chemicals, and oxidative stress. The ability to adapt to these …

Variations in climate conditions can dramatically affect plant health and the generation of
climate-resilient crops is imperative to food security. In addition to directly affecting plants, it …

Pathogenic bacteria can detect a variety of environmental signals, including temperature
changes. While sudden and significant temperature variations act as danger signals that …

The transmissible locus of stress tolerance (tLST) is found mainly in beta-and gamma-
Proteobacteria and confers tolerance to elevated temperature, pressure, and chlorine. This …