Gut microbiota interacts with inflammatory responses in acute pancreatitis

L Wu, J Hu, X Yi, J Lv, J Yao, W Tang… - Therapeutic …, 2023 - journals.sagepub.com
Acute pancreatitis (AP) is one of the most common acute abdominal conditions, and its
incidence has been increasing for years. Approximately 15–20% of patients develop severe …

P66shc and its role in ischemic cardiovascular diseases

K Boengler, J Bornbaum, KD Schlüter… - Basic Research in …, 2019 - Springer
Oxidative stress caused by an imbalance in the formation and removal of reactive oxygen
species (ROS) plays an important role in the development of several cardiovascular …

Beef, casein, and soy proteins differentially affect lipid metabolism, triglycerides accumulation and gut microbiota of high-fat diet-fed C57BL/6J mice

MU Ijaz, MI Ahmed, X Zou, M Hussain… - Frontiers in …, 2018 - frontiersin.org
Consumption of dietary protein at recommended levels is considered a potential strategy to
promote satiety and weight management, but how protein from different dietary sources …

Antibiotics-induced perturbations in gut microbial diversity influence metabolic phenotypes in a murine model of high-fat diet-induced obesity

D Liu, B Wen, K Zhu, Y Luo, J Li, Y Li, H Lin… - Applied Microbiology …, 2019 - Springer
Gut microbiota play a key role in the regulation of obesity and associated metabolic
disorders. To study the relationship between them, antibiotics have been widely used to …

The role of p66Shc in diabetes: a comprehensive review from bench to bedside

SF Mousavi, MA Khazeei Tabari… - Journal of Diabetes …, 2022 - Wiley Online Library
It is well‐documented that diabetes is an inflammatory and oxidative disease, with an
escalating global burden. Still, there is no definite treatment for diabetes or even prevention …

Epigenetic remodeling in obesity-related vascular disease

S Masi, S Ambrosini, SA Mohammed… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: The prevalence of obesity and cardiometabolic phenotypes is alarmingly
increasing across the globe and is associated with atherosclerotic vascular complications …

Extending lifespan by modulating the growth hormone/insulin-like growth factor-1 axis: coming of age

S Duran-Ortiz, EO List, R Basu, JJ Kopchick - Pituitary, 2021 - Springer
Progress made in the years of aging research have allowed the opportunity to explore
potential interventions to slow aging and extend healthy lifespan. Studies performed in …

[HTML][HTML] The role of the redox enzyme p66Shc in biological aging of the lung

CFG Castro, C Nardiello, S Hadzic… - Aging and …, 2024 - ncbi.nlm.nih.gov
The mitochondrial adaptor protein p66Shc has been suggested to control life span in mice
via the release of hydrogen peroxide. However, the role of p66Shc in lung aging remains …

Shared postulations between bipolar disorder and polycystic ovary syndrome pathologies

W Dai, J Liu, Y Qiu, Z Teng, S Li, J Huang… - Progress in Neuro …, 2022 - Elsevier
Introduction Women with bipolar disorder (BD) present a high prevalence of polycystic ovary
syndrome (PCOS) and other reproductive disorders even before diagnosis or treatment of …

Modulation of Obesity and Insulin Resistance by the Redox Enzyme and Adaptor Protein p66Shc

S Ciciliot, GP Fadini - International Journal of Molecular Sciences, 2019 - mdpi.com
Initially reported as a longevity-related protein, the 66 kDa isoform of the mammalian Shc1
locus has been implicated in several metabolic pathways, being able to act both as an …