The cascade of metastasis in tumor cells, exhibiting organ-specific tendencies, may occur at
numerous phases of the disease and progress under intense evolutionary pressures. Organ …

Single-cell technologies have enabled the characterization of the tumour microenvironment
at unprecedented depth and have revealed vast cellular diversity among tumour cells and …

Leptomeningeal metastasis (LM), or spread of cancer to the cerebrospinal fluid (CSF)–filled
space surrounding the central nervous system, is a fatal complication of cancer. Entry into …

Bioenergetic perturbations driving neoplastic growth increase the production of reactive
oxygen species (ROS), requiring a compensatory increase in ROS scavengers to limit …

Simple Summary Leptomeningeal metastases are a devastating complication of solid
tumors with poor survival, regardless of the type of treatments. The limited efficacy of …

Purpose Circulating tumor cells in cerebrospinal fluid are a quantitative diagnostic tool for
leptomeningeal metastases from solid tumors, but their prognostic significance is unclear …

Glioblastoma (GB) and brain metastases (BM) are the most common brain tumors in adults
and are invariably associated with a dismal outcome. These highly malignant tumors share …

Simple Summary The prevalence of breast cancer brain metastasis has increased over the
last decades, yet those patients are considered untreatable. Surgical removal of brain …

Optical approaches to monitor neural activity are transforming neuroscience, owing to a fast-
evolving palette of genetically encoded molecular reporters. However, the field still requires …

Cold‑inducible RNA‑binding protein (CIRBP) is a cold‑shock protein comprised of an RNA‑
binding motif that is induced by several stressors, such as cold shock, UV radiation, nutrient …