Intussusceptive angiogenesis is a dynamic intravascular process capable of dramatically
modifying the structure of the microcirculation. The distinctive structural feature of …

In European countries, nearly 10% of all hospital admissions are related to respiratory
diseases, mainly chronic life-threatening diseases such as COPD, pulmonary hypertension …

Idiopathic pulmonary fibrosis (IPF) is characterized by chronic inflammation, severe scarring,
and stem cell senescence. Stem cell-based therapies modulate inflammatory and fibrogenic …

To investigate the role of immune cells in lung regeneration, we used a unilateral
pneumonectomy model that promotes the formation of new alveoli in the remaining lobes …

A wide range of cardiac symptoms have been observed in COVID-19 patients, often
significantly influencing the clinical outcome. While the pathophysiology of pulmonary …

Abstract Extracellular matrix protein 1 (ECM1) is related to strong invasiveness and poor
prognosis in major malignancies, but the underlying mechanism remains unknown. Here we …

Nitrogen mustard (NM) is an alkylating agent known to cause extensive pulmonary injury
progressing to fibrosis. This is accompanied by a persistent macrophage inflammatory …

The simplification of alveoli leads to various lung pathologies such as bronchopulmonary
dysplasia and emphysema. Deep insight into the process of emergence of the secondary …

Recent studies have identified epithelial stem and progenitor cell populations of the lung.
We are just beginning to understand the mechanisms that regulate their homeostatic …

Chronic degenerative lung diseases are essentially untreatable pathological conditions. By
contrast, the healthy lung has numerous mechanisms that allow for rapid repair and …