Krebs von den Lungen-6 (KL-6) as a diagnostic marker for pulmonary fibrosis: A systematic review and meta-analysis

C Wang, Q Wang, T Liu, J Zhu, B Zhang - Clinical Biochemistry, 2023 - Elsevier
Background Pulmonary fibrosis (PF) is a respiratory disease with end-stage pathological
changes of interstitial lung disease that severely affects the survival of patients. Among the …

[HTML][HTML] The role of epithelial cells in fibrosis: mechanisms and treatment

L Luo, W Zhang, S You, X Cui, H Tu, Q Yi, J Wu… - Pharmacological …, 2024 - Elsevier
Fibrosis is a pathological process that affects multiple organs and is considered one of the
major causes of morbidity and mortality in multiple diseases, resulting in an enormous …

Circulating inflammatory cytokines and risk of idiopathic pulmonary fibrosis: a Mendelian randomization study

Q Jia, Y Lei, S Chen, S Liu, T Wang, Y Cheng - BMC Pulmonary Medicine, 2023 - Springer
Background The previous epidemiological and experimental evidence has implied the
linkage between chronic inflammation to idiopathic pulmonary fibrosis (IPF). However, it was …

High sodium intake increases interstitial lung disease and pulmonary sarcoidosis based on the Global Burden of Disease study 1999–2019

Z Hu, Y Tian, A Yang, X Song - Scientific Reports, 2024 - nature.com
This study investigated the relationships between dietary sodium intake and the incidence
and prevalence of interstitial lung disease (ILD) and pulmonary sarcoidosis using data from …

[HTML][HTML] Deciphering the molecular mechanisms of Maxing Huoqiao Decoction in treating pulmonary fibrosis via transcriptional profiling and circRNA-miRNA-mRNA …

C Zhao, E Bu, C Zhang, R Lai, J He, B Guo, W Guo… - Phytomedicine, 2023 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic interstitial
lung condition with unknown etiology and high mortality. Chinese herbal medicine has been …

1β-Hydroxyalantolactone from Inulae Flos alleviated the progression of pulmonary fibrosis via inhibiting JNK/FOXO1/NF-κB pathway

B Yu, XQ Jin, WY Yu, YY Dong, HZ Ying… - International …, 2021 - Elsevier
Inulae Flos was widely distributed throughout Europe, Africa, and Asia, and was commonly
used as a folk medicine in clinic for treating various respiratory diseases, including cough …

Current perspective of progressive-fibrosing interstitial lung disease

T Kishaba - Respiratory Investigation, 2022 - Elsevier
Interstitial lung disease (ILD) is a parenchymal lung disease and restrictive disorder that
presents as diffuse infiltrative shadows. The initial diagnosis of ILD is important because …

Cyclophilin A regulates the apoptosis of A549 cells by stabilizing Twist1 protein

Y Wu, Z Ma, Y Zhang, M Zhang, W Zhang… - Journal of Cell …, 2022 - journals.biologists.com
Cyclophilin A (CypA, also known as PPIA) is an essential member of the immunophilin
family. As an intracellular target of the immunosuppressive drug cyclosporin A (CsA) or a …

[HTML][HTML] A novel therapeutic approach for IPF: Based on the “Autophagy-Apoptosis” balance regulation of Zukamu Granules in alveolar macrophages

S Li, G Liu, M Gu, Y Li, Y Li, Z Ji, K Li, Y Wang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Zukamu Granules (ZKMG) is one of the
representative Uygur patent drugs widely used in China, which is included in the National …

Tanshinone IIA Alleviates Pulmonary Fibrosis by Inhibiting Pyroptosis of Alveolar Epithelial Cells Through the MAPK Signaling Pathway

Y Xu, Y Wang, W Peng, H Bu, Y Zhou… - Phytotherapy …, 2025 - Wiley Online Library
The current dearth of safe and efficacious pharmaceutical interventions for pulmonary
fibrosis (PF) has prompted investigations into alternative treatments. This study aim to …