Laboratory studies involving repeated exposure to paraquat (PQ) in different animal models
can induce many of the pathological features of Parkinson's disease (PD), such as the loss …

Paraquat, a cationic herbicide, produces degenerative lesions in the lung and in the nervous
system after systemic administration to man and animals. Many cases of acute poisoning …

Deltamethrin and thiachloprid are an α-cyano class pyrethroid and neonicotinoid insecticide,
respectively. Recently, a pesticide combining deltamethrin and thiacloprid has also been …

Paraquat (PQ), a widely used herbicide is a well-known free radical producing agent. The
mechanistic pathways of PQ neurotoxicity were examined by assessing oxidative/nitrosative …

Oxidative stress is implicated in Parkinson's disease (PD). Metallothioneins (MT),
cytochrome P450 IIE1 (CYP2E1) and glutathione S-transferases alpha4-4 (GSTA4-4) are …

Oxidative stress plays a crucial role in the manifestations of maneb (MB) and paraquat (PQ)-
induced toxicity including MB+ PQ-induced Parkinson's disease (PD). Polymorphonuclear …

The study aimed to investigate the effects of atrazine (ATR), chlorpyrifos (CPF), and the
mixture of them on nitric oxide (NO) and inducible nitric oxide synthase (iNOS) in the brain of …

The precise mechanism underlying the role of nitric oxide (NO) or nitric oxide synthases
(NOSs) in paraquat-mediated toxicity is yet to be fully elucidated. The importance of the …

Paraquat (PQ) is a well-known herbicide that exerts its effects by elevating intracellular
levels of superoxide. It has been previously demonstrated that oxidative and nitrosative …

The use of the herbicide paraquat (1, 1'-dimethyl-4, 4'-bipyridylium dichloride; PQ) which is
widely used in agriculture is known to cause dopaminergic neurotoxicity. However, the …