The isolation-biological activities (2014–2022), bio, semi, total synthesis (1978–2022) and SAR studies of a potential naturally engineered scaffold aristolactam

MC Reddy, A Dey, M Jeganmohan… - New Journal of Chemistry, 2023 - pubs.rsc.org
Aristolactams are a small group of aporphinoid alkaloids containing the phenanthrene
chromophore that were first isolated from Aristolochia argentina (Aristolochiaceae), which is …

New analogues of aporphine alkaloids

YC Ge, KW Wang - Mini reviews in medicinal chemistry, 2018 - ingentaconnect.com
Aporphine alkaloids, characterized by a heterocyclic aromatic basic skeleton, are known
from different organisms and exhibit various biological activities: anti-tumor, anti-viral, anti …

Cell cycle arrest and apoptosis induction by methanolic leaves extracts of four Annonaceae plants

K Pumiputavon, T Chaowasku, C Saenjum… - … and Alternative Medicine, 2017 - Springer
Abstract Background Uvaria longipes (Craib) LL Zhou, YCF Su & RMK Saunders, Artabotrys
burmanicus A. DC, Marsypopetalum modestum (Pierre) B. Xue & RMK Saunders and …

[HTML][HTML] Aristolactam BIII, a naturally derived DYRK1A inhibitor, rescues Down syndrome-related phenotypes

M Choi, A Kim, Y Ham, JY Lee, D Kim, A Yang, MJ Jo… - Phytomedicine, 2021 - Elsevier
Background Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a
significant pathogenic factor in Down syndrome (DS), wherein DYRK1A is overexpressed by …

[HTML][HTML] Isolation and characterization of aristolactam alkaloids from the stem bark of Goniothalamus velutinus (Airy Shaw) and their biological activities

E Iqbal, LBL Lim, KA Salim, S Faizi, A Ahmed… - Journal of King Saud …, 2018 - Elsevier
Phytochemical investigation on a crude methanolic bark extract of Goniothalamus velutinus
resulted in the isolation of four compounds, aristolactam I (1), aristolactam BII (2) …

Antioxidant, anti-rheumatic and anti-inflammatory investigation of extract and dicentrinone from Duguetia furfuracea (A. St.-Hil.) Benth. & Hook. f.

RC do Santos, AV de Souza, M Andrade-Silva… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance The preparations of teas and syrups using Duguetia
furfuracea have been used in folk medicine to treat rheumatism and back pain. Several …

Polyoxygenated cyclohexene derivatives isolated from Dasymaschalon sootepense and their biological activities

S Hongthong, C Kuhakarn, T Jaipetch, S Prabpai… - Fitoterapia, 2015 - Elsevier
Six new naturally occurring polyoxygenated cyclohexene derivatives together with eight
related known derivatives, two known alkaloids, and two known flavonoid derivatives were …

In vitro nephrotoxicity and structure-toxicity relationships of eight natural aristolactams

S Xue, W Bao, J Lyu, C Wang, Y Zhang, H Li, D Chen… - Toxicon, 2025 - Elsevier
The structural similarity between aristolactams (ALs) and aristolochic acids (AAs) raises
constant concerns about the safety of ALs-containing plants. Natural ALs are distributed …

[PDF][PDF] Cytotoxic activity of alkaloids from Papaver rhoeas growing in Lebanon

MA Hijazi, M Aboul-Ela, K Bouhadir, M Fatfat… - Rec. Nat. Prod, 2017 - acgpubs.org
This paper represents the phytochemical properties of Lebanese Papaver rhoeas, from
which five protopine alkaloids are isolated, namely; stylopine (1), canadine (2), sinactine (3) …

Cytotoxic and Antimalarial Alkaloids from the Twigs of Dasymaschalon obtusipetalum

A Jaidee, T Promchai, K Trisuwan… - Natural Product …, 2015 - journals.sagepub.com
One new p-quinonoid aporphine alkaloid, obtusipetadione (1), and eleven known
compounds (2–12) were isolated from the acetone extract of the twigs of Dasymaschalon …