Cyclodextrins improving the physicochemical and pharmacological properties of antidepressant drugs: a patent review

TC Diniz, TCC Pinto, PP Menezes… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Depression is a serious mood disorder and is one of the most common mental
illnesses. Despite the availability of several classes of antidepressants, a substantial …

Vitamin A Palmitate–β-cyclodextrin inclusion complexes: Characterization, protection and emulsification properties

N Vilanova, C Solans - Food chemistry, 2015 - Elsevier
The interest in the production of foods enriched with vitamins, in order to prevent diseases
related with their deficiency, has recently increased. However, the low stability and the low …

Biperiden Hydrochloride/β-Cyclodextrins supramolecular system and its cytotoxicity against lung adenocarcinoma cells

BBM Vieira, I Lula, NM Leão, DCF Soares… - Journal of Molecular …, 2023 - Elsevier
Understanding the supramolecular structures and the host and guest interactions of
supramolecular systems is crucial to corroborate the biological findings. In this sense …

Inclusion complexes of β and HPβ-cyclodextrin with α, β amyrin and in vitro anti-inflammatory activity

WF da Silva Júnior, DL Bezerra de Menezes… - Biomolecules, 2019 - mdpi.com
α, β amyrin (ABAM) is a natural mixture of pentacyclic triterpenes that has a wide range of
biological activities. ABAM is isolated from the species of the Burseraceae family, in which …

Inclusion Complexes of Copaiba (Copaifera multijuga Hayne) Oleoresin and Cyclodextrins: Physicochemical Characterization and Anti-Inflammatory Activity

JGO Pinheiro, EA Tavares, SS Silva… - International journal of …, 2017 - mdpi.com
Complexation with cyclodextrins (CDs) is a technique that has been extensively used to
increase the aqueous solubility of oils and improve their stability. In addition, this technique …

Advancing insights on β-cyclodextrin inclusion complexes with SSRIs through lens of X-ray diffraction and DFT calculation

T Aree - International Journal of Pharmaceutics, 2021 - Elsevier
Depression—the global crisis hastened by the coronavirus outbreak, can be efficaciously
treated by the selective serotonin reuptake inhibitors (SSRIs). Cyclodextrin (CD) inclusion …

Inclusion scenarios and conformational flexibility of the SSRI paroxetine as perceived from polymorphism of β-cyclodextrin–paroxetine complex

T Aree - Pharmaceuticals, 2022 - mdpi.com
Depression, a global mental health problem, is prevalent during the coronavirus disease
2019 (COVID-19) pandemic and can be efficiently treated by selective serotonin reuptake …

Solid-state characterization of sertraline base–β-cyclodextrin inclusion complex

N Ogawa, T Hashimoto, T Furuishi, H Nagase… - … of Pharmaceutical and …, 2015 - Elsevier
Sertraline is one of the serotonin-specific reuptake inhibitors that is effective in treating
several disorders such as major depression, obsessive–compulsive disorder, panic …

Erlotinib/hydroxypropyl-β-cyclodextrin inclusion complex: characterization and in vitro and in vivo evaluation

SML Gontijo, PPG Guimarães, CTR Viana… - Journal of Inclusion …, 2015 - Springer
Erlotinib (ERL) is a drug used in epidermoid carcinoma treatment. One of the ERL
drawbacks is low water solubility, which limits its use in the development of safer and …

Electrochemical determination of sertraline in pharmaceutical formulation and serum using a gold electrode in a pH 8.4 bicarbonate solution

J Lović, J Lađarević, N Trišović, F Andrić… - Monatshefte für Chemie …, 2021 - Springer
The electrochemical characterization of sertraline at gold electrode was examined by cyclic
voltammetry measurements (CV) in pH 8.4 bicarbonate buffer. Then Au electrode was …