How pyroptosis contributes to inflammation and fibroblast-macrophage cross-talk in rheumatoid arthritis
About thirty years ago, a new form of pro-inflammatory lytic cell death was observed and
termed pyroptosis. Only in 2015, gasdermins were defined as molecules that create pores at …
termed pyroptosis. Only in 2015, gasdermins were defined as molecules that create pores at …
RSAD2 is abundant in atherosclerotic plaques and promotes interferon-induced CXCR3-chemokines in human smooth muscle cells
A Hayderi, AK Kumawat, VS Shavva, M Dreifaldt… - Scientific Reports, 2024 - nature.com
In atherosclerotic lesions, monocyte-derived macrophages are major source of interferon
gamma (IFN-γ), a pleotropic cytokine known to regulate the expression of numerous genes …
gamma (IFN-γ), a pleotropic cytokine known to regulate the expression of numerous genes …