Next-generation sequencing (NGS) technologies have recently developed beyond the
research realm and started to mature into clinical applications. Here, we review the current …

Next-generation sequencing (NGS) has become a widely used technology in biological
research. NGS applications for clinical pathogen detection have become vital technologies …

Background The early diagnosis of sepsis is hampered by the lack of reliable laboratory
measures. There is growing evidence that presepsin and Mid-regional pro-adrenomedullin …

Next-generation sequencing (NGS) has emerged as a promising tool for diagnosing fungal
infections. It enables the identification of a wide range of fungal species and provides more …

Methods: The Next GeneSiPS-Trial is a prospective, observational, non-interventional,
multicenter study used to assess the diagnostic performance of an NGS-based approach for …

Background: After liver transplantation (LTX), patients are susceptible to opportunistic
infections resulting in reduced outcomes within the early post-transplantation period. The …

The therapy of gastrointestinal carcinomas includes surgery, chemo-or immunotherapy, and
radiation with diverse complications such as surgical-site infection and enteritis. In recent …

Next-generation sequencing (NGS) has been further optimised during the last years and has
given us new insights into the human microbiome. The 16S rDNA sequencing, especially, is …

Purpose Infections are common complications in patients following liver transplantation
(LTX). The early diagnosis and prognosis of these infections is an unmet medical need even …

Invasive fungal diseases (IFDs) remain important causes of high morbidity and mortality in
many immunosuppressed patients. Accurate etiology diagnosis coupled with subsequent …