Lactose is one of the most widespread excipients used in the pharmaceutical industry.
Because of its water solubility and acceptable flowability, lactose is generally added into …

Preformulation studies like storage, transfer, fluidisation, and compaction, are subject to the
excellent flowability of the powder. It is often required for proper operational management …

Background The conventional oral dosage forms are not effective in dealing with
chronopathological conditions, such as nocturnal asthma. Therefore, there is an unmet need …

Application of numerical simulations are desired to improve the quality of powder products
and to optimize the production process in powder die-filling. In the powder die-filling …

Powder flow is a critical attribute of pharmaceutical blends to ensure tablet weight uniformity
and production of tablets with consistent and reproducible properties. This study aims at …

The die filing process within a lab-scale rotary tablet press is simulated using the Discrete
Element Method (DEM). Powder is transferred from a gravity feeder (comprising of a …

Purpose Understanding and predicting the flow of bulk pharmaceutical materials could be
key in enabling pharmaceutical manufacturing by continuous direct compression (CDC) …

In the pharmaceutical industry, powder flowability is an essential manufacturability attribute
to consider when selecting the suitable manufacturing route and formulation. The selection …

Dynamic avalanche testing is a newer method useful even with cohesive powder samples.
To evaluate flow properties of pharmaceutical powder excipients, break energy (BE) is …

Rotary tabletting presses are widely used to produce tablets in the pharmaceutical industry.
In the tabletting process using a rotary press, rotary die filling is one of critical process steps …