Polyphenols as antitumor agents targeting key players in cancer-driving signaling pathways

MH Cháirez-Ramírez, KG de la Cruz-López… - Frontiers in …, 2021 - frontiersin.org
Polyphenols constitute an important group of natural products that are traditionally
associated with a wide range of bioactivities. These are usually found in low concentrations …

In vivo gene delivery mediated by non-viral vectors for cancer therapy

R Mohammadinejad, A Dehshahri… - Journal of Controlled …, 2020 - Elsevier
Gene therapy by expression constructs or down-regulation of certain genes has shown great
potential for the treatment of various diseases. The wide clinical application of nucleic acid …

Curcumin delivery mediated by bio-based nanoparticles: a review

M Moballegh Nasery, B Abadi, D Poormoghadam… - Molecules, 2020 - mdpi.com
Todays, nano-pharmaceutics is emerging as an important field of science to develop and
improve efficacy of different drugs. Although nutraceuticals are currently being utilized in the …

[HTML][HTML] Targeted regulation of autophagy using nanoparticles: New insight into cancer therapy

MDA Paskeh, M Entezari, C Clark, A Zabolian… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Normal cells depend on autophagy to maintain cellular homeostasis by recycling damaged
organelles and misfolded proteins and degrading toxic agents. Similar to apoptosis …

Metformin Attenuates Silica-Induced Pulmonary Fibrosis by Activating Autophagy via the AMPK-mTOR Signaling Pathway

S Li, C Li, X Pang, J Zhang, G Yu, AJ Yeo… - Frontiers in …, 2021 - frontiersin.org
Long-term exposure to crystalline silica particles leads to silicosis characterized by
persistent inflammation and progressive fibrosis in the lung. So far, there is no specific …

Multifunctional polymeric nanoplatforms for brain diseases diagnosis, therapy and theranostics

S Shakeri, M Ashrafizadeh, A Zarrabi, R Roghanian… - Biomedicines, 2020 - mdpi.com
The blood–brain barrier (BBB) acts as a barrier to prevent the central nervous system (CNS)
from damage by substances that originate from the blood circulation. The BBB limits drug …

Chitosan-based advanced materials for docetaxel and paclitaxel delivery: Recent advances and future directions in cancer theranostics

M Ashrafizadeh, Z Ahmadi, N Mohamadi… - International journal of …, 2020 - Elsevier
Paclitaxel (PTX) and docetaxel (DTX) are key members of taxanes with high anti-tumor
activity against various cancer cells. These chemotherapeutic agents suffer from a number of …

Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response

M Ashrafizadeh, MDA Paskeh, S Mirzaei… - Journal of Experimental …, 2022 - Springer
Prostate cancer is a leading cause of death worldwide and new estimates revealed prostate
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …

Anti-tumor activity of resveratrol against gastric cancer: A review of recent advances with an emphasis on molecular pathways

M Ashrafizadeh, H Rafiei, R Mohammadinejad… - Cancer Cell …, 2021 - Springer
Gastric cancer (GC) is one of the most common cancers with high malignancy. In spite of the
great development in diagnostic tools and application of anti-tumor drugs, we have not …

Functionalization of polymers and nanomaterials for biomedical applications: Antimicrobial platforms and drug carriers

M Delfi, M Ghomi, A Zarrabi, R Mohammadinejad… - Prosthesis, 2020 - mdpi.com
The use of polymers and nanomaterials has vastly grown for industrial and biomedical
sectors during last years. Before any designation or selection of polymers and their …