▪ Abstract Neurotrophins are a family of growth factors critical for the development and
functioning of the nervous system. Although originally identified as neuronal survival factors …

There is a pressing need for treatments for neurodegenerative diseases. Hopes have been
raised by the prospect of neural stem cell therapy; however, despite intense research …

The multilineage differentiation capacity of mouse embryonic stem (ES) cells offers a
potential testing platform for gene products that mediate mammalian lineage determination …

The transcription factor Sox1 is the earliest and most specific known marker for mammalian
neural progenitors. During fetal development, Sox1 is expressed by proliferating progenitor …

A complex orchestration of stem-cell specification, expansion and differentiation is required
for the proper development of the nervous system. Although progress has been made on the …

Background Recurrent implantation failure is a critical issue in IVF‐ET treatment. Successful
embryo implantation needs appropriate molecular and cellular communications between …

The mammal Shc locus encodes three overlapping isoforms (46, 52, and 66 kDa) that differ
in the length of their N-terminal regions. p46/p52Shc and p66Shc have been implicated …

Peroxisome proliferator-activated receptor γ (PPARγ) plays an important role in insulin
sensitivity, tissue homeostasis, and regulating cellular functions. We found high-level …

Oligodendrogliomas are brain tumors accounting for approximately 10% of all central
nervous system cancers. CIC is a transcription factor that is mutated in most patients with …

Developmental arrest is one of the mechanisms responsible for the elevated levels of
embryo demise during the first week of in vitro development. Approximately 10–15% of IVF …