Computational methodologies are assisting the exploration of marine natural products
(MNPs) to make the discovery of new leads more efficient, to repurpose known MNPs, to …

Microorganisms are the dominating source of food and nutrition for sponges and play an
important role in sponge structure, chemical defense, excretion and evolution. In recent …

Sorbicillinoids are important hexaketide metabolites derived from fungi. They have a variety
of biological activities including cytotoxic, antioxidant, antiviral and antimicrobial activity. The …

The microsporidian Enterocytozoon hepatopenaei (EHP) is an emerging pathogen that
causes substantial economic losses in shrimp (Penaeus spp.) aquaculture worldwide. To …

A series of trisubstituted indolizine analogues has been designed as a result of a fragment-
based approach to target the inhibition of mycobacterial enoyl-acyl carrier protein reductase …

Coaggregation plays an important role in the development of multispecies biofilms in
different environments, often serving as an active bridge between biofilm members and …

Background: The treatment of infection caused by pathogenic bacteria becomes one of the
serious concerns globally. The failure in the treatment was found due to the exhibition of …

Recently, people worldwide have experienced several outbreaks caused by viruses that
have attracted much interest globally, such as HIV, Zika, Ebola, and the one being faced …

Abstract The marine sponge Haliclona (Reniera) sp. was a potential source of natural
bioactive compounds. This sponge widely distributed along the coast of Panjang Island …

Background: Lactic acid bacteria produce various beneficial metabolites, including
antimicrobial agents. Owing to the fast-rising antibiotic resistance among pathogenic …