Myocardial work index: a marker of left ventricular contractility in pressure‐or volume overload‐induced heart failure

BK Lakatos, M Ruppert, M Tokodi, A Oláh… - ESC Heart …, 2021 - Wiley Online Library
Aims While global longitudinal strain (GLS) is considered to be a sensitive marker of left
ventricular (LV) function, it is significantly influenced by loading conditions. We hypothesized …

[HTML][HTML] Longitudinal strain reflects ventriculoarterial coupling rather than mere contractility in rat models of hemodynamic overload–induced heart failure

M Ruppert, BK Lakatos, S Braun, M Tokodi… - Journal of the American …, 2020 - Elsevier
Background Longitudinal strain (LS) is a sensitive marker of systolic function. Recent
findings suggest that both myocardial contractility and loading conditions determine LS. The …

Protection of sacubitril/valsartan against pathological cardiac remodeling by inhibiting the NLRP3 inflammasome after relief of pressure overload in mice

X Li, Q Zhu, Q Wang, Q Zhang, Y Zheng… - … drugs and therapy, 2020 - Springer
Background/aims The persistent existence of pathological cardiac remodeling, resulting
from aortic stenosis, is related to poor clinical prognosis after successful transcatheter aortic …

Sex similarities and differences in the reverse and anti-remodeling effect of pressure unloading therapy in a rat model of aortic banding and debanding

M Ruppert, BA Barta, S Korkmaz-Icöz… - American Journal …, 2022 - journals.physiology.org
Investigating the effect of sex on pressure unloading therapy in a clinical scenario is limited
by several nonstandardized factors. Hence, we sought to study sex-related similarities and …

Pressure overload-induced systolic heart failure is associated with characteristic myocardial microRNA expression signature and post-transcriptional gene regulation …

M Ruppert, S Korkmaz-Icöz, B Benczik, B Ágg… - Scientific Reports, 2023 - nature.com
Although systolic function characteristically shows gradual impairment in pressure overload
(PO)-evoked left ventricular (LV) hypertrophy (LVH), rapid progression to congestive heart …

Non-invasive myocardial work as an independent predictor of postprocedural NT-proBNP in elderly patients undergoing transcatheter aortic valve replacement

Z Ladányi, T Bálint, A Fábián, A Ujvári, TK Turschl… - GeroScience, 2024 - Springer
Aortic stenosis has become the most prevalent valvular disease with increasing life
expectancy and the ageing of the population, representing a significant clinical burden for …

Multi-Omic, Histopathologic, and Clinicopathologic Effects of Once-Weekly Oral Rapamycin in a Naturally Occurring Feline Model of Hypertrophic Cardiomyopathy: A …

VN Rivas, JL Kaplan, SA Kennedy, S Fitzgerald… - Animals, 2023 - mdpi.com
Simple Summary Hypertrophic cardiomyopathy (HCM) is the single most common
cardiomyopathy in cats with no available therapeutic options in the asymptomatic period of …

Effect of danqi buxin decoction on chronic function indexes and life quality in patients with chronic heart failure of yang deficiency type

Y Sheng, H Qiu, S Chen - Evidence‐Based Complementary …, 2021 - Wiley Online Library
Objective. The purpose was to explore the clinical effect of Danqi Buxin decoction on chronic
heart failure (CHF) with yang deficiency and its effect on cardiac function and life quality of …

Global longitudinal strain in moderate aortic stenosis: a chance to synthesize it all?

BK Lakatos, A Kovács - Circulation: Cardiovascular Imaging, 2020 - Am Heart Assoc
Myocardial ischemia (by the often coexisting coronary artery disease) lowers contractility. Of
note, the results presented by the authors highlight that reduced GLS was associated with …

[HTML][HTML] E/e'比值与射血分数改善型心衰患者预后的相关性研究

马玉骁, 刘立春, 高娟, 曹丽华, 朱娟娟… - Advances in Clinical …, 2023 - hanspub.org
目的: 探讨E/e'比值在射血分数改善型心力衰竭(HFimpEF) 患者中的预后价值. 方法: 收集2019
年1 月~ 2022 年1 月因HFrEF 在青岛大学附属医院心血管内科住院的患者 …