Colorectal cancer (CRC) is one of the most frequently occurring malignancy tumors with a
high morbidity additionally, CRC patients may develop liver metastasis, which is the major …

Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …

Pyroptosis is a newly discovered programmed cell death that is associated with tumor
progression, prognosis, and treatment response. However, the potential roles of pyroptosis …

Abstract Rationale: Tumor-associated macrophages (TAMs), generally displaying the pro-
tumor M2-like phenotype, strongly influence the progression of colorectal cancer (CRC) via …

Macrophages play a crucial role in immune activation and provide great value in the
prognosis of cancer treatments. Current strategies for prognostic evaluation of macrophages …

Macrophages are the most abundant and one of the most critical cells of tumor immunity.
They provide a bridge between innate and adaptive immunity through releasing cytokines …

The macrophages are abundantly found in TME and their M2 polarization is in favor of tumor
malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage …

Purpose: While evidence indicates that Fusobacterium nucleatum (F. nucleatum) may
promote colorectal carcinogenesis through its suppressive effect on T-cell–mediated …

It is often difficult to regain neurological function following spinal cord injury (SCI).
Neuroinflammation is thought to be responsible for this failure. Regulating the inflammatory …

Pancreatic ductal adenocarcinoma (PDAC) is projected to become the second leading
cause of cancer-related death. Hallmarks include desmoplasia with variable extracellular …