Insulin resistance is a cardiovascular risk factor in humans

MM Adeva-Andany, J Martínez-Rodríguez… - Diabetes & Metabolic …, 2019 - Elsevier
Diabetes is a common metabolic disorder associated to elevated cardiovascular morbidity
and mortality that is not explained by hyperglycemia or traditional cardiovascular risk factors …

Modifiable risk factors for cardiovascular disease in children with type 1 diabetes: can early intervention prevent future cardiovascular events?

E Gourgari, D Dabelea, K Rother - Current diabetes reports, 2017 - Springer
Abstract Purpose of Review Patients with type 1 diabetes have increased risk for
cardiovascular disease. The purpose of this review is to examine the following: i) current …

Early changes in cardiovascular structure and function in adolescents with type 1 diabetes

TJ Bradley, C Slorach, FH Mahmud, DB Dunger… - Cardiovascular …, 2016 - Springer
Background Children with type 1 diabetes (T1D) are at higher risk of early adult-onset
cardiovascular disease. We assessed cardiovascular structure and function in adolescents …

Youth with type 1 diabetes have adipose, hepatic, and peripheral insulin resistance

M Cree-Green, JJ Stuppy, J Thurston… - The Journal of …, 2018 - academic.oup.com
Context Adolescents with type 1 diabetes (T1D) have difficulty obtaining optimal glucose
control, which may relate to insulin resistance (IR), especially during puberty. Moreover, IR …

Nutrition and obesity in the pathogenesis of youth-onset type 1 diabetes and its complications

CA March, DJ Becker, IM Libman - Frontiers in Endocrinology, 2021 - frontiersin.org
Since the 1980s, there has been a dramatic rise in the prevalence of overweight and obesity
in pediatric populations, in large part driven by sedentary lifestyles and changing dietary …

Exercise effects on arterial stiffness and heart health in children with excess weight: The SMART RCT

CL Davis, SE Litwin, NK Pollock, JL Waller… - International journal of …, 2020 - nature.com
Introduction Childhood obesity and inactivity are associated with cardiovascular risk.
Evidence is limited for exercise effects on arterial health in children. Methods One hundred …

Longitudinal changes in arterial stiffness and heart rate variability in youth-onset type 1 versus type 2 diabetes: the SEARCH for diabetes in youth study

AS Shah, S Isom, R D'Agostino Jr, LM Dolan… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE We compared arterial stiffness and heart rate variability (HRV) over time by
diabetes type and determined the risk factors associated with worsening arterial stiffness …

Impact of insulin resistance on cardiac and vascular function

G Novo, G Manno, R Russo, D Buccheri… - International Journal of …, 2016 - Elsevier
Background Insulin resistance (IR), constitutes an important cardiovascular risk factor and
can cause ischemic heart disease. It can lead to left ventricular dysfunction with a …

Predictors of increased carotid intima-media thickness in youth with type 1 diabetes: the SEARCH CVD study

AS Shah, D Dabelea, NF Fino, LM Dolan… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE Youth with type 1 diabetes have worse cardiovascular (CV) risk factors and
higher carotid intima-media thickness (IMT) than their peers without diabetes. Whether the …

Cardiovascular disease in young People with type 1 diabetes: search for cardiovascular biomarkers

M Schäfer, KJ Nadeau, JEB Reusch - Journal of diabetes and its …, 2020 - Elsevier
Premature onset of cardiovascular disease is common in people with type 1 diabetes and is
relatively understudied in youth. Several reports in adolescents and young adults with …