Challenges and opportunities for consistent classification of human B cell and plasma cell populations

I Sanz, C Wei, SA Jenks, KS Cashman… - Frontiers in …, 2019 - frontiersin.org
The increasingly recognized role of different types of B cells and plasma cells in protective
and pathogenic immune responses combined with technological advances have generated …

Age-associated B cells in autoimmune diseases

IC Mouat, E Goldberg, MS Horwitz - Cellular and Molecular Life Sciences, 2022 - Springer
Age-associated B cells (ABCs) are a transcriptionally and functionally unique B cell
population. In addition to arising with age and following infection, ABCs are expanded …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Guidelines for the use of flow cytometry and cell sorting in immunological studies*

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2017 - Wiley Online Library
From a technical point of view a flow cytometer is a light detection device capable of
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …

Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice

KM Nickerson, S Smita, KB Hoehn… - Journal of Experimental …, 2023 - rupress.org
Age-associated B cells (ABCs) are formed under inflammatory conditions and are
considered a type of memory B cell (MBC) expressing the transcription factor T-bet. In SLE …

[HTML][HTML] Myalgic encephalomyelitis/chronic fatigue syndrome–evidence for an autoimmune disease

F Sotzny, J Blanco, E Capelli, J Castro-Marrero… - Autoimmunity …, 2018 - Elsevier
Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a frequent and
severe chronic disease drastically impairing life quality. The underlying pathomechanism is …

Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus

CM Tipton, CF Fucile, J Darce, A Chida, T Ichikawa… - Nature …, 2015 - nature.com
Acute systemic lupus erythematosus (SLE) courses with surges of antibody-secreting cells
(ASCs) whose origin, diversity and contribution to serum autoantibodies remain unknown …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

B cell immunosenescence

D Frasca, A Diaz, M Romero, D Garcia… - Annual review of cell …, 2020 - annualreviews.org
Innate and adaptive immune responses decline with age, leading to greater susceptibility to
infectious diseases and reduced responses to vaccines. Diseases are more severe in old …

Morbidity and mortality in common variable immune deficiency over 4 decades

ES Resnick, EL Moshier, JH Godbold… - Blood, The Journal …, 2012 - ashpublications.org
The demographics, immunologic parameters, medical complications, and mortality statistics
from 473 subjects with common variable immune deficiency followed over 4 decades in New …