Although known for over 90 years, only in the past two decades has the chemistry of diboron
(4) compounds been extensively explored. Many interesting structural features and reaction …

In recent years, the pharmaceutical market has experienced a paradigm shift; as small
molecules had long been thought of as the ultimate therapeutics, the use of biologics …

Natural product synthesis is a highly demanding field in constant need of efficient
transformations that allow either straightforward, scalable, and high-yielding preparation of …

The utility of copper-mediated cross-coupling reactions has been significantly increased by
the development of mild reaction conditions and the ability to employ catalytic amounts of …

Organotrifluoroborates represent an alternative to boronic acids, boronate esters, and
organoboranes for use in Suzuki− Miyaura and other transition-metal-catalyzed cross …

Organometallic reagents (RM) are of increasing importance not only for organometallic
chemists but also in organic chemistry and pharmaceutical synthesis and to access organic …

The discovery of the copper-promoted Chan-Lam coupling reaction with boronic acids more
than ten years ago has greatly advanced the carbon-heteroatom cross-coupling chemistry …

Monocoordinated palladium catalysts derived from sterically hindered, electron‐rich
phosphines or N‐heterocyclic carbenes have revolutionized the Suzuki–Miyaura coupling …

Peptide modifications can unlock a variety of compounds with structural diversity and
abundant biological activity. In nature, peptide modifications, such as functionalisation at the …

Though often perceived as the simple metaphorical hybrid of synthetic inorganic and
organic chemistry, synthetic organometallic chemistry continues to vigorously differentiate …