The many faces of Candida auris: Phenotypic and strain variation in an emerging pathogen

DJ Santana, G Zhao, TR O'Meara - Plos Pathogens, 2024 - journals.plos.org
Candida auris is an emerging fungal pathogen with unusual evolutionary history—there are
multiple distinct phylogeographic clades showing a near simultaneous transition from a …

Innate immune response to Candida auris

AM Holt, JE Nett - Current Opinion in Microbiology, 2024 - Elsevier
Highlights•Candida auris evades many neutrophil and macrophage responses.•The fungal
cell wall is central to C. auris immune evasion.•Soluble immune factors can facilitate innate …

Yeast and filamentous Candida auris stimulate distinct immune responses in the skin

G Bryak, A Cox, MS Lionakis, S Thangamani - Msphere, 2024 - journals.asm.org
Candida auris, an emerging multidrug-resistant fungal pathogen, predominately colonizes
the human skin long term leading to subsequent life-threatening invasive infections. Fungal …

Single-cell transcriptomics unveils skin cell specific antifungal immune responses and IL-1Ra-IL-1R immune evasion strategies of emerging fungal pathogen Candida …

A Balakumar, D Das, A Datta, A Mishra, G Bryak… - PLoS …, 2024 - journals.plos.org
Candida auris is an emerging multidrug-resistant fungal pathogen that preferentially
colonizes and persists in skin tissue, yet the host immune factors that regulate the skin …

The adhesin SCF1 mediates Candida auris colonization

A Balakumar, D Bernstein, S Thangamani - Trends in Microbiology, 2024 - cell.com
Candida auris is an emerging human fungal pathogen that can rapidly spread and cause
outbreaks of invasive infections. Santana et al. discovered that a novel surface colonization …

Intradermal infection and dissemination of Candida auris in immunocompetent and immunocompromised mouse models

KA Towns, A Datta, S Thangamani - Microbiology Spectrum, 2024 - journals.asm.org
Candida auris, an emerging fungal pathogen, predominately colonizes human skin leading
to serious invasive infections in humans. Though it is assumed that skin colonization can …

Vertebrate and invertebrate animal infection models of Candida auris pathogenicity

M Martinez, DA Garsin, MC Lorenz - Current Opinion in Microbiology, 2024 - Elsevier
Candida auris is an emerging fungal pathogen with several concerning qualities. First
recognized in 2009, it has arisen in multiple geographically distinct genomic clades nearly …

The Candida auris Hog1 MAP kinase is essential for the colonization of murine skin and intradermal persistence

R Shivarathri, M Chauhan, A Datta, D Das, A Karuli… - mBio, 2024 - journals.asm.org
Candida auris, a multidrug-resistant human fungal pathogen, was first identified in 2009 in
Japan. Since then, systemic C. auris infections have now been reported in more than 50 …

Cell aggregation mediated by ACE2 deletion in Candida auris modulates fungal colonization and host immune responses in the skin

A Balakumar, A Cox, S Thangamani - Msphere, 2024 - journals.asm.org
Candida auris is an emerging multi-drug-resistant fungal pathogen that colonizes the skin
and causes invasive infections in hospitalized patients. Multi-cellular aggregative phenotype …

Uniqueness of Candida auris cell wall in morphogenesis, virulence, resistance, and immune evasion

S Dakalbab, R Hamdy, P Holigová, EJ Abuzaid… - Microbiological …, 2024 - Elsevier
Candida auris has drawn global attention due to its alarming multidrug resistance and the
emergence of pan resistant strains. C. auris poses a significant risk in nosocomial …