Deep brain stimulation has been extensively studied as a therapeutic option for treatment-
resistant depression (TRD). DBS across different targets is associated with on average 60 …

Although deep brain stimulation (DBS) is an established treatment choice for Parkinson's
disease (PD), essential tremor and movement disorders, its effectiveness for the …

Major depressive disorder (MDD) is a widespread, severe, debilitating disorder that
markedly diminishes quality of life. Medication is commonly effective, but 20–30% of patients …

Non-invasive brain stimulation is designed to target accessible brain regions that underlie
many psychiatric disorders. One such method, transcranial magnetic stimulation (TMS), is …

Most chronic stress protocols are too laborious or do not abide by the two main
characteristics of the stress concept: uncontrollability and unpredictability. The goal of this …

Background Deep brain stimulation (DBS) delivered to the ventromedial prefrontal cortex
(vmPFC) induces antidepressant-and anxiolytic-like responses in various animal models …

The use of deep brain stimulation (DBS) for the treatment of chronic pain was one of the first
applications of this technique in functional neurosurgery. Established brain targets in the …

Major depression contributes significantly to the global disability burden. Since the first
clinical study of deep brain stimulation (DBS), over 446 patients with depression have now …

Both selective serotonin reuptake inhibitors (SSRIs) and ventromedial prefrontal cortex
(vmPFC) deep brain stimulation (DBS) modulate serotonergic activity. We compared the …

Background Treatment-resistant depression (TRD) occurs more commonly in women. Deep
brain stimulation (DBS) is an emerging treatment for TRD, and its efficacy continues to be …